Protein Alignment Tao and CDKL4

DIOPT Version :9

• Sequence 1: NP_001188672.1
• Gene: Tao / 32948
• FlyBaseID: FBgn0031030
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_001333840.1
• Gene: CDKL4 / 344387
• HGNCID: 19287
• Length: 379
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 81/285 - (28%)
• Similarity: 139/285 - (48%)
• Gaps: 35/285 - (12%)

  Fly    27 FEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTIEYK 91
            :|.|.:.|.||:|.|:..|...:.::||:||...:......| :..|:|||.|:||.|||.:...
Human     4 YEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVK-KIALREIRMLKQLKHPNLVNLI 67

  Fly    92 GCYLRESTAWLVMEYCVGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRIHRDIKAGNI 156
            ..:.|:....||.|||..:..:.:|.:...:.:..|.::....|..|::.|....||||||..||
Human    68 EVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENI 132

  Fly   157 LLTDNGVVKLADFGSAAIKCPANS---FVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELA 218
            |:|..|::|:.|||.|.|..|.::   :|.|.::.|||:::.  :.||...||:|::|....||.
Human   133 LITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVG--DTQYGSSVDIWAIGCVFAELL 195

  Fly   219 ERKPPYFNMNAMSALYHIAQNESPTLPKND--------------------------WSDAF---C 254
            ..:|.:...:.:..||.|.:.....:|::.                          :||..   .
Human   196 TGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGISIPEPEDMETLEEKFSDVHPVAL 260

  Fly   255 SFVELCLKKMPAERPSSAKLLTHAY 279
            :|::.|||..|.:|.:.::||..:|
Human   261 NFMKGCLKMNPDDRLTCSQLLESSY 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	81/285 (28%)
		S_TKc	27..280	CDD:214567	81/285 (28%)
CDKL4	NP_001333840.1	[NKR]KIAxRE	45..51		2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910