DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tao and pak2b

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_001020627.1	Gene:	pak2b / 325034	ZFINID:	ZDB-GENE-030131-3759	Length:	539	Species:	Danio rerio

Alignment Length:	309	Identity:	118/309 - (38%)
Similarity:	169/309 - (54%)	Gaps:	20/309 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RP--GSLKDPEIAD----LFNKHDPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGK 63
            ||  |.:.|.||.|    :.:..||:|.:....:||.|:.|.|:.|....|.:.||||:::.
Zfish   236 RPKKGKMTDEEIMDKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTAIDVATGQEVAIKQINL--- 297

  Fly    64 QSQEKWQDILKEIRFLRQLNHPNTIEYKGCYLRESTAWLVMEYCV-GSASDIIEVHKKPLHEDEI 127
            |.|.|.:.|:.||..:::|.:||.:.:...:|.....::||||.. ||.:|:  |.:..:.|.:|
Zfish   298 QKQPKKELIINEILVMKELKNPNIVNFLDSFLVGEELFVVMEYLAGGSLTDV--VTETCMDEAQI 360

  Fly   128 AAICLGVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCPANS----FVGTPYWM 188
            ||:|...|..|.:||:...||||||:.|:||..:|.|||.|||..|...|..|    .|||||||
Zfish   361 AAVCRECLQALEFLHANQVIHRDIKSDNVLLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWM 425

  Fly   189 APEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNESPTLPKND-WSDA 252
            ||||:   ....|..|||:|||||..||:.|.:|||.|.|.:.|||.||.|.:|.|...: .|..
Zfish   426 APEVV---TRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQSPEKLSPI 487

  Fly   253 FCSFVELCLKKMPAERPSSAKLLTHAYVTRPRSDTVLLELIARTKSAVR 301
            |..|:..||:....:|..|.:||.|.::...:..:.|..||...|.|::
Zfish   488 FRDFLGRCLEMDVEKRGGSKELLQHPFLKLAKPLSSLTPLILAAKDAMK 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	104/262 (40%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	103/258 (40%)
pak2b	NP_001020627.1	PBD	74..129	CDD:279166
		STKc_PAK2	244..539	CDD:132986	115/301 (38%)
		S_TKc	264..515	CDD:214567	103/258 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910