DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tao and Map3k20

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	XP_038962299.1	Gene:	Map3k20 / 311743	RGDID:	1561394	Length:	802	Species:	Rattus norvegicus

Alignment Length:	316	Identity:	86/316 - (27%)
Similarity:	147/316 - (46%)	Gaps:	53/316 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 FEDLR---EIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTI 88
            |:||:   ..|.||||:||.|:.....:.||:||:           ..|.||...|..|:|.|.|
  Rat    13 FDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-----------LKIEKEAEILSVLSHRNVI 66

  Fly    89 EYKGCYLRESTAWLVMEYC-VGSASDIIEVHK-KPLHEDEIAAICLGVLSGLSYLH---SLGRIH 148
            ::.|..|......:|.||. :||..|.|..:: :.:..:.|......|..|:.|||   .:..||
  Rat    67 QFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIH 131

  Fly   149 RDIKAGNILLTDNGVVKLADFGSAAIKCPAN--SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLG 211
            ||:|:.|:::..:||:|:.|||::.......  |.|||..|||||||.::...:   ..|.:|.|
  Rat   132 RDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSE---TCDTYSYG 193

  Fly   212 ITCIELAERKPPYFNMNAMSALYHIAQ-NESPTLPKNDWSDAFC--SFVEL---CLKKMPAERPS 270
            :...|:..|:.|:..:..:...:.:.: ||..|:|.:      |  ||.||   |.:....:|||
  Rat   194 VVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSS------CPRSFAELLHQCWEADAKKRPS 252

  Fly   271 SAKLLTHAYVTRPRSDTVLLELIARTKSAVRELDNLNYRKMKKILMVDTCETESAV 326
            ..::::            :||.::...:...:.::..:.|.:.     .||.|:.:
  Rat   253 FKQIIS------------ILESMSNDTNLPDQCNSFLHNKAEW-----RCEIEATL 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	80/270 (30%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	80/268 (30%)
Map3k20	XP_038962299.1	STKc_MLTK	22..263	CDD:270962	79/272 (29%)
Map3k20	XP_038962299.1	SAM_MLTK	338..408	CDD:188928
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910