Protein Alignment Tao and Stk10

DIOPT Version :9

• Sequence 1: NP_001188672.1
• Gene: Tao / 32948
• FlyBaseID: FBgn0031030
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_062079.2
• Gene: Stk10 / 29398
• RGDID: 3779
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 1057
• Identity: 277/1057 - (26%)
• Similarity: 467/1057 - (44%)
• Gaps: 220/1057 - (20%)

  Fly    22 DPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPN 86
            ||..::|.|.|:|.|:||.||.|:...|..:.|.|.:.   .:|:|:.:|.:.||..|...:||.
  Rat    31 DPNDVWEILGELGDGAFGKVYKAKNKETGALAAAKVIE---TKSEEELEDYIVEIEILATCDHPY 92

  Fly    87 TIEYKGCYLRESTAWLVMEYCVGSASDIIEVH-KKPLHEDEIAAICLGVLSGLSYLHSLGRIHRD 150
            .::..|.|..:...|:::|:|.|.|.|.|.:. .:.|.|.:|..:|..:|..|::||....||||
  Rat    93 IVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRD 157

  Fly   151 IKAGNILLTDNGVVKLADFGSAAIKCPA----NSFVGTPYWMAPEVIL--AMDEGQYDGKVDVWS 209
            :||||:|:|..|.::|||||.:|.....    :||:||||||||||:|  .|.:..||.|.|:||
  Rat   158 LKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWS 222

  Fly   210 LGITCIELAERKPPYFNMNAMSALYHIAQNESPT-LPKNDWSDAFCSFVELCLKKMPAERPSSAK 273
            ||||.||:|:.:||:..:|.|..|..||:::.|| |..:.||..|..|:::.|.|.|..|||:|:
  Rat   223 LGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSTEFRDFLKIALDKNPETRPSAAQ 287

  Fly   274 LLTHAYVTRPRSDTVLLELIARTKSAVRELDNLNYRKMKKILMVDTCETESAVGDTDDQQDDHAG 338
            ||.|.:|:...|:..|.||:|..|:.|.|                  |.|.  |..|.::|....
  Rat   288 LLQHPFVSTVTSNKALRELVAEAKAEVME------------------EIED--GKEDGREDGRED 332

  Fly   339 GDSSKSNSITSEHSIHSVGVSAASSQSSSSNSIPAAAQNHHHIAAHHHQQAASAAVAAAMHHHHH 403
            |:....:   .:.::.:|......:|.||:|....:..:...:      |.:|..:
  Rat   333 GEEEDGD---EKDAVSAVPPPVNHTQDSSANGTQPSLNSDKLL------QDSSTPL--------- 379

  Fly   404 PHQQP------PPSWPSGQQGQP---VPPGAVSRNSS-------RHRNRPPLPNIMHSMNNNVTP 452
            |..||      |.:.||| .|.|   .|...||:|.:       ..::||      .|::..:..
  Rat   380 PPSQPQEPVNGPCNQPSG-DGSPQNTSPADEVSKNDNGLKVPVPLRKSRP------LSVDARIQV 437

  Fly   453 TNSASVVPA---PAPAPVLPPPIS-VLPHLSAMGHVG-----GGGTGTGGSGGGSPASGGPLADR 508
            |....:...   |:.|...||.:: ..|:.||:..:|     .||....||
  Rat   438 TEEKQITDQAENPSSAASKPPKVNQSRPNSSALETLGVETLANGGLELPGS-------------- 488

  Fly   509 IQPVQPRYLTTPAAQAAVYAASSASSQQAISNAVNDHGPNNFA---------------------- 551
                     .||.........|:.|:.:::     |:|.:..|
  Rat   489 ---------VTPNHSKRASDCSNLSTSESM-----DYGTSLSADLSLNKETGSLSLKGSKLHNKT 539

  Fly   552 --------------TIRTTSIVTKQQKEHMQEEM----HEQMSGYKRMRREHQAHLVKLEEKCKV 598
                          :|.|:.|:::.:|:  .|||    .:::...:.:::|...:..:|..|.::
  Rat   540 LKRTRRFVVDGVEVSITTSKIISEDEKK--DEEMRFLRRQELRELRLLQKEEHRNQTQLSTKHEL 602

  Fly   599 DMEAHKTALDKEYDTLLHNFTRDLDRLETKHQQDVERRAKQTSAAEKKLHKEITLKQENDRKVYD 663
            .:|......::|.:.....:..:|:.||.:.:|.||:..:..|...::..|.|.|:|:.|...:.
  Rat   603 QLEQMHRRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRREEAKRIRLEQDRDYARFQ 667

  Fly   664 ---LNRKKEYKANKERWKRELSMDESTPKRQRDLTLQSQKDNLKQHEAQEEQRMLQAQKQYIELE 725
               ...|||.|...||..|. |.:.|        :.|.|.:: .|...:.::..:..||:.:||.
  Rat   668 EQLKQMKKEVKLTVERLARN-SRNSS--------SFQEQTEH-PQAARRRDRDFVAKQKEDLELA 722

  Fly   726 MRKF--KRKRMIMQHEHEDQQLRDELGKKEQQLQQAHAMLLKHHEKTQELEYRQQKSVHQLREEQ 788
            |:|.  :.:|.|...|      ||.|.||::.|:...|.|       .|:|..|.:..|||.::|
  Rat   723 MKKLTAENRREICDKE------RDCLNKKQELLRDREAAL-------WEMEEHQLQERHQLVKQQ 774

  Fly   789 INKQHDTELHNQKDYMDRIKKELVRKHAVELRQQPKSLKQK---ELQIRKQ---------FRETC 841
            :..|:..:.|           :|:|||..| |:|.:...|:   :|::|:|         .|...
  Rat   775 LKDQYFLQRH-----------DLLRKHEKE-REQMQRYNQRMMEQLKVRQQQEKARLPKIQRSDG 827

  Fly   842 KTQTKQYKRYKAQVLQTTPKEQQKEVIKQL--KEEKHRKLTLLGEQ--YEQSIADMFQSQSYKLD 902
            ||:...||: ...:.......:|:|.:||.  :|||.:|...|.:|  :|..:.||.......::
  Rat   828 KTRMAMYKK-SLHINGAGSASEQREKVKQFSQQEEKRQKAERLQQQQKHENQMRDMVAQCESNMN 891

  Fly   903 ESQVIECQRTHEQLEYELEMLTAYQNKNKKQAQEQRDRERRELENRVSVRRGLLENKMDAELQQF 967
            |.|.::.::.|..:|:|.:.|.|....:.:..:|.||:.|        .|:..||.    :|.|.
  Rat   892 ELQQLQNEKCHLLVEHETQKLKALDESHNQSLKEWRDKLR--------PRKKALEE----DLNQK 944

  Fly   968 NQERAERLRMKHEKHTK 984
            .:|:....|:..|..|:
  Rat   945 KREQEMFFRLSEEAETR 961

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	107/264 (41%)
		S_TKc	27..280	CDD:214567	106/260 (41%)
Stk10	NP_062079.2	STKc_STK10	23..314	CDD:132975	115/285 (40%)
		S_TKc	36..294	CDD:214567	106/260 (41%)
		PKK	600..738	CDD:289257	34/147 (23%)
		PKK	768..908	CDD:289257	39/152 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910