DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tao and pak2a

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_001002717.1	Gene:	pak2a / 266749	ZFINID:	ZDB-GENE-021011-2	Length:	517	Species:	Danio rerio

Alignment Length:	305	Identity:	115/305 - (37%)
Similarity:	166/305 - (54%)	Gaps:	18/305 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GSLKDPEIAD----LFNKHDPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQE 67
            |.:.|.||.:    :.:..||:|.:....:||.|:.|.||.|....|.:.||||:::.   |.|.
Zfish   218 GKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVYTAIDVATGQEVAIKQINL---QKQP 279

  Fly    68 KWQDILKEIRFLRQLNHPNTIEYKGCYLRESTAWLVMEYCV-GSASDIIEVHKKPLHEDEIAAIC 131
            |.:.|:.||..:::|.:||.:.:...:|.....::||||.. ||.:|:  |.:..:.|.:|||:|
Zfish   280 KKELIINEILVMKELKNPNIVNFLDSFLVGDELFVVMEYLAGGSLTDV--VTETCMDEAQIAAVC 342

  Fly   132 LGVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCPANS----FVGTPYWMAPEV 192
            ...|..|.:||:...||||||:.|:||..:|.|||.|||..|...|..|    .|||||||||||
Zfish   343 RECLQALEFLHANQVIHRDIKSDNVLLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 407

  Fly   193 ILAMDEGQYDGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNESPTLPKND-WSDAFCSF 256
            :   ....|..|||:|||||..||:.|.:|||.|.|.:.|||.||.|.:|.|...: .|..|..|
Zfish   408 V---TRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDF 469

  Fly   257 VELCLKKMPAERPSSAKLLTHAYVTRPRSDTVLLELIARTKSAVR 301
            :..||:....:|....:||.|.::...:..:.|..||...|.|::
Zfish   470 LNRCLEMDVEKRGGGKELLQHPFLKLAKPLSSLTPLILAAKEAMK 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	104/262 (40%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	103/258 (40%)
pak2a	NP_001002717.1	PBD	74..129	CDD:279166
		STKc_PAK2	222..517	CDD:132986	114/301 (38%)
		S_TKc	242..493	CDD:214567	103/258 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910