Protein Alignment Tao and Stk10

DIOPT Version :9

• Sequence 1: NP_001188672.1
• Gene: Tao / 32948
• FlyBaseID: FBgn0031030
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_033314.2
• Gene: Stk10 / 20868
• MGIID: 1099439
• Length: 966
• Species: Mus musculus
• Alignment Length: 1044
• Identity: 276/1044 - (26%)
• Similarity: 467/1044 - (44%)
• Gaps: 221/1044 - (21%)

  Fly    22 DPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPN 86
            ||..::|.:.|:|.|:||.||.|:...|..:.|.|.:.   .:|:|:.:|.:.||..|...:||.
Mouse    31 DPNDVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIE---TKSEEELEDYIVEIEILATCDHPY 92

  Fly    87 TIEYKGCYLRESTAWLVMEYCVGSASDIIEVH-KKPLHEDEIAAICLGVLSGLSYLHSLGRIHRD 150
            .::..|.|..:...|:::|:|.|.|.|.|.:. .:.|.|.:|..:|..:|..|::||....||||
Mouse    93 IVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRD 157

  Fly   151 IKAGNILLTDNGVVKLADFGSAAIKCPA----NSFVGTPYWMAPEVIL--AMDEGQYDGKVDVWS 209
            :||||:|:|..|.::|||||.:|.....    :||:||||||||||:|  .|.:..||.|.|:||
Mouse   158 LKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWS 222

  Fly   210 LGITCIELAERKPPYFNMNAMSALYHIAQNESPT-LPKNDWSDAFCSFVELCLKKMPAERPSSAK 273
            ||||.||:|:.:||:..:|.|..|..||:::.|| |..:.||..|..|:::.|.|.|..|||:|:
Mouse   223 LGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQ 287

  Fly   274 LLTHAYVTRPRSDTVLLELIARTKSAVRELDNLNYRKMKKILMVDTCETESAVGDTDDQQDDHAG 338
            ||.|.:|:|..|:..|.||:|..|:.|.|                         :.:|.::|...
Mouse   288 LLQHPFVSRVTSNKALRELVAEAKAEVME-------------------------EIEDGREDGEE 327

  Fly   339 GDSSKSNSITSEHSIHSVGVSAASSQSS---SSNSIPAAAQNHHHIAAHHHQQAASAAVAAAMHH 400
            .|:..:......|:..|..|:..|..|:   ..:|.|.
Mouse   328 EDAVDAVPPLVNHTQDSANVTQPSLDSNKLLQDSSTPL--------------------------- 365

  Fly   401 HHHPHQQPPPSWP----SGQQGQPVPPGAVSRNS-----SRHRN--RPPLP---NIMHSMNNNVT 451
                    |||.|    ||...||...|.:...|     |::.|  :.|:|   :...||:..:.
Mouse   366 --------PPSQPQEPVSGSCSQPSGDGPLQTTSPADGLSKNDNDLKVPVPLRKSRPLSMDARIQ 422

  Fly   452 PTNSASVV-----PAPAPAPVLPPPISVLPHLSAMGHVGGGGTGTGGSGGGSPASGGPLADRIQP 511
            ......:.     |:||.:.......| .|:.||:..:||.....||.  ..|:|
Mouse   423 MDEEKQIPDQDENPSPAASKSQKANQS-RPNSSALETLGGEALTNGGL--ELPSS---------- 474

  Fly   512 VQPRYLTTPAAQAAVYAASSASSQQAISNAVNDHGPNNFA------------------------- 551
                  .||:........|:.|:.:::     |:|.:..|
Mouse   475 ------VTPSHSKRASDCSNLSTSESM-----DYGTSLSADLSLNKETGSLSLKGSKLHNKTLKR 528

  Fly   552 -----------TIRTTSIVTKQQKEHMQEEM----HEQMSGYKRMRREHQAHLVKLEEKCKVDME 601
                       :|.|:.|:::.:|:  .|||    .:::...:.:::|...:..:|..|.::.:|
Mouse   529 TRRFVVDGVEVSITTSKIISEDEKK--DEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLE 591

  Fly   602 AHKTALDKEYDTLLHNFTRDLDRLETKHQQDVERRAKQTSAAEKKLHKEITLKQENDRKVYDLNR 666
            ......::|.:.....:..:|:.||.:.:|.||:..:..|...|:..|.|.|:|:.|...:
Mouse   592 QMHKRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRKEEAKRIRLEQDRDYAKF---- 652

  Fly   667 KKEYKANKERWKRELSMDESTPKRQRDLTLQSQKDNLKQHEAQEEQRM----LQAQKQYIELEMR 727
            :::.|..|:..|.|:   |..|::||.   :|.|..:::| :|::||:    :..||:.:||.||
Mouse   653 QEQLKQMKKEVKSEV---EKLPRQQRK---ESMKQKMEEH-SQKKQRLDRDFVAKQKEDLELAMR 710

  Fly   728 KF--KRKRMIMQHEHEDQQLRDELGKKEQQLQQAHAMLLKHHEKTQELEYRQQKSVHQLREEQIN 790
            |.  :.:|.|...|      ||.|.||::.|:...|.|       .|:|..|.:..|||.::|:.
Mouse   711 KLTTENRREICDKE------RDCLSKKQELLRDREAAL-------WEMEEHQLQERHQLVKQQLK 762

  Fly   791 KQHDTELHNQKDYMDRIKKELVRKHAVELRQQPKSLKQK---ELQIRKQ---------FRETCKT 843
            .|:..:.|           :|:|||..| |:|.:...|:   :|::|:|         .|...||
Mouse   763 DQYFLQRH-----------DLLRKHEKE-REQMQRYNQRMMEQLKVRQQQEKARLPKIQRSDGKT 815

  Fly   844 QTKQYKRYKAQVLQTTPKEQQKEVIKQL--KEEKHRKLTLLGEQ--YEQSIADMFQSQSYKLDES 904
            :...||: ...:.......:|:|.|||.  :|||.:|...|.:|  :|..:.||.......:.|.
Mouse   816 RMAMYKK-SLHINGAGSASEQREKIKQFSQQEEKRQKAERLQQQQKHENQMRDMVAQCESNMSEL 879

  Fly   905 QVIECQRTHEQLEYELEMLTAYQNKNKKQAQEQRDRERRELENRVSVRRGLLENKMDAELQQFNQ 969
            |.::.::.|..:|:|.:.|.|....:.:..:|.||:.|   ..:.::...|.:.|.:.|:.....
Mouse   880 QQLQNEKCHLLVEHETQKLKALDESHNQSLKEWRDKLR---PRKKALEEDLNQKKREQEMFFKLS 941

  Fly   970 ERAE 973
            |.||
Mouse   942 EEAE 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	106/264 (40%)
		S_TKc	27..280	CDD:214567	105/260 (40%)
Stk10	NP_033314.2	STKc_STK10	23..314	CDD:132975	115/285 (40%)
		S_TKc	36..294	CDD:214567	105/260 (40%)
		Activation segment. /evidence=ECO:0000250	175..224		24/48 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..497		39/214 (18%)
		PKK	586..724	CDD:289257	38/148 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	660..692		11/38 (29%)
		PKK	754..894	CDD:289257	40/152 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	826..865		12/38 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	901..966		10/48 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910