DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tao and pak-2

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_505809.2	Gene:	pak-2 / 179527	WormBaseID:	WBGene00006443	Length:	522	Species:	Caenorhabditis elegans

Alignment Length:	285	Identity:	98/285 - (34%)
Similarity:	145/285 - (50%)	Gaps:	18/285 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPN 86
            ||.....|.::||.||.|.|..|....|::|||:|:|:...:|.:|.   :..|:..|||..|||
Worm   226 DPRSDLTDYKQIGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRREL---LFNEVSILRQYQHPN 287

  Fly    87 TIEYKGCYLRESTAWLVMEYCV-GSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRIHRD 150
            .:.:...:|.:...|:|||:.. ||.:||:...:  :.|.:||.|...||..|.:||:...||||
Worm   288 IVRFFSSHLVDDELWVVMEFMEGGSLTDIVTATR--MTEPQIATISRQVLGALDFLHARKVIHRD 350

  Fly   151 IKAGNILLTDNGVVKLADF---GSAAIKCP-ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLG 211
            ||:.:|||..:|.|||.||   |..:.:.| ..|.||||||.|.|||.   ...||.:.|:||.|
Worm   351 IKSDSILLKRDGTVKLTDFGFCGQLSEEVPRRRSLVGTPYWTAAEVIA---REPYDTRADIWSFG 412

  Fly   212 ITCIELAERKPPYFNMNAMSALYHIAQNESPTLPKN-DWSDAFCSFVELCLKKMPAERPSSAKLL 275
            |..||:.|.:||:||.....|:..|.........:: ..|......:..|:.|...:|..:..||
Worm   413 IMLIEMVEGEPPFFNDQPFQAMKRIRDEHEARFSRHAKVSVELSELLSHCIVKDVNKRWPAKDLL 477

  Fly   276 THAYVTRPRSDT----VLLELIART 296
            .|.:..:.:..:    :||:|...|
Worm   478 RHPFFAKAQHSSSIAPLLLQLQGNT 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	92/262 (35%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	92/258 (36%)
pak-2	NP_505809.2	CRIB_PAK_like	14..60	CDD:238526
		PKc_like	223..483	CDD:304357	94/264 (36%)
		S_TKc	232..482	CDD:214567	92/257 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910