DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tao and AgaP_AGAP003174

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	XP_312866.5	Gene:	AgaP_AGAP003174 / 1273841	VectorBaseID:	AGAP003174	Length:	1355	Species:	Anopheles gambiae

Alignment Length:	970	Identity:	199/970 - (20%)
Similarity:	342/970 - (35%)	Gaps:	229/970 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 FEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTIEYK 91
            |:.::::|.|::|.|.......|.:.||||.:..:..:::.....|.:|::.:..:.|||.|...
Mosquito    53 FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKSKIETEADLIRIRREVQIMSSVQHPNIIHIY 117

  Fly    92 GCYLRESTAWLVMEYCVGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRIHRDIKAGNI 156
            ..:.......||||:..|.........:|.|.|:|...|...|.:.:.|.|.....|||:|..||
Mosquito   118 EVFENREKMVLVMEFAAGGELYDYLSERKVLAEEEARRIFRQVSTAIYYCHKHKICHRDLKLENI 182

  Fly   157 LLTDNGVVKLADFGSAAI---KCPANSFVGTPYWMAPEVILAMDEGQYDG-KVDVWSLGITCIEL 217
            ||.::|..|:||||.:.:   :....:|.|:|.:.:||::...   .|.| :||.||||:....|
Mosquito   183 LLDEHGNAKIADFGLSNVFDEQRLLATFCGSPLYASPEIVKGT---PYQGPEVDCWSLGVLLYTL 244

  Fly   218 AERKPPYFNMNAMSALYHIAQNE--SPTLPKNDWSDAFCSFVELCLKKMPAERPSSAKLLTHAYV 280
            .....|:...|....:..|:|.:  .|..|... |......:.:|    |:.|.:..::..|.:|
Mosquito   245 VYGAMPFDGANFKRLVKQISQGDYFEPKKPSRA-SPLIREMLTVC----PSHRANIEQICNHWWV 304

  Fly   281 ------------------TRPRSDTVLLELI-----------------ARTKSAVRELDNLNYRK 310
                              |..|.| |||.|.                 |:.|..::     ....
Mosquito   305 NEGYEESCLDLAEELANQTPVRLD-VLLSLAPPSVTADQLLVGNGQEDAKAKDRIQ-----RSHS 363

  Fly   311 MKKILMVDTCETESAVGDTDDQQDDHAGGDS----SKSNSITSEHSIHSVGVSAASSQS------ 365
            |..|:.:...|.|..:.|.     ..|||::    |.:.:||...:..:.||.:..:|:
Mosquito   364 MGSIVEMGGTEAERRILDM-----VAAGGEAALMPSPTRTITPAEAATAAGVGSPQAQTKRKLET 423

  Fly   366 --SSSNSI-----------PAAAQNHHHIAAHHHQQAASAAVAAAMHHHHHPHQQPPPSWPSGQQ 417
              |:.|:.           |:.||    ...........||||..........|...|..|:.|:
Mosquito   424 TVSTENATGAVKKKDKADPPSPAQ----ARIPEDMDVEEAAVAGTPTQAAADEQTAEPVQPTAQE 484

  Fly   418 GQPVP-PGAVSRNSSRHRNRPPLPNIMHSMNN-NVTPTNSASVVPAPAPA----PVLPPPISVLP 476
            ....| ..|...|.|:...:..|.::.:..|. :.....:|...|.|:.|    .:.|||.|  |
Mosquito   485 EATKPSDSAAQPNESKFEAQEVLEDLQNLENMCDELLLEAAHTQPPPSEAGANGAIEPPPSS--P 547

  Fly   477 HLSAMGHVGGG----GTGTGGSGGGSPASGGPLADRIQPVQPRYLTTPAAQAAVYAASSASSQQA 537
            .:..:..|...    ..|..|:....|:|..||              |..: .|:..:..:....
Mosquito   548 PVKTVSSVRAKLEKLEKGEIGAKPAVPSSTAPL--------------PTVR-KVFGKNKTTDLTT 597

  Fly   538 ISNAVNDHGPNNFATIRTTSIVTKQQKEHMQEEMHEQMSGYKRMRREHQAHLVKLEEKCKVDMEA 602
            ..|.||               ..|.:...:....|...|..:|........|.:..|:.|
Mosquito   598 AINEVN---------------ARKGEPALLAGSAHRSASSVERKNSLPDESLARTAERRK----- 642

  Fly   603 HKTALDKEYDTLLHNFTRDLDRLETKHQQDVERRAKQTSAAEKKLHKEITLKQENDRKVYDLNRK 667
                            :|.|:..| |.||   ...:|....:|  .|:..|.......|.  |.|
Mosquito   643 ----------------SRILETAE-KFQQ---LNQQQPGGGDK--FKKFVLPGGGVPTVG--NYK 683

  Fly   668 KEYKANKERWKRELSMDESTPKRQRDLTLQS---------------------QKDNLKQHEAQEE 711
            ||:       :|:..:..|:...:...|.|:                     ...||..::.|::
Mosquito   684 KEF-------ERKTGLSTSSTFTKPPATPQATTTGEGESGGSAPSTPPAFAGSAKNLATYQQQQQ 741

  Fly   712 QRM------LQAQKQYIELEMRKFKRKRMIMQHEHEDQQLRDELGKKEQQLQQAHAMLLKHHEKT 770
            |:.      |.|.|.  :.|:::...|..:.....||.:         :.::.:.|||.:  .|.
Mosquito   742 QQQGTDSPPLAATKS--DDEVKESDSKSSVGSFSLEDAR---------RSMENSIAMLSR--AKP 793

  Fly   771 QELEYRQQKSVHQL--REEQINKQHDTE----LHNQKDYM-DRIKKELVRKHAVELRQQPKSLKQ 828
            .:.......::.||  |.|.::...|:|    |.|.::.: :.|....:||..:......:| ..
Mosquito   794 NDSAPSTPTAIDQLCARTESVSMMEDSERERKLKNAREIIGNAIPIGRLRKPPMPFGANGRS-TT 857

  Fly   829 KELQIRKQFR---ET----CKTQTKQYKRYKAQVLQTTPKEQQKEVIKQLKEEKHRKLTL 881
            ..|.|.|.:|   ||    |.|.:.. ::.....:.:.||::.|        ..|.::||
Mosquito   858 GTLGINKPYRMGSETPEPRCDTMSIP-RKVSIGSIPSPPKDETK--------TSHAEITL 908

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	69/278 (25%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	68/258 (26%)
AgaP_AGAP003174	XP_312866.5	STKc_NUAK	51..304	CDD:270975	68/258 (26%)
AgaP_AGAP003174	XP_312866.5	S_TKc	53..304	CDD:214567	68/258 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910