DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tao and lats2

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	XP_012811721.1	Gene:	lats2 / 100124721	XenbaseID:	XB-GENE-994907	Length:	1117	Species:	Xenopus tropicalis

Alignment Length:	262	Identity:	62/262 - (23%)
Similarity:	106/262 - (40%)	Gaps:	66/262 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTI 88
            :.:|..::.:|.|:||.|..|....|:.:.|:|.:......::.:...:..|...|.:.::...:
Frog   695 KSLFVKIKTLGIGAFGEVCLASKVDTKALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVV 759

  Fly    89 EYKGCYLRESTAWLVMEYCVGSASDI------IEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRI 147
            :....:..:.:.:.||:|..|  .|:      :||..:.|....||.:.|.:.|    :|.:|.|
Frog   760 KLYYSFQDKDSLYFVMDYIPG--GDMMSLLIRMEVFPEHLARFYIAELTLAIES----VHKMGFI 818

  Fly   148 HRDIKAGNILLTDNGVVKLADFGSAA--------------------------------------- 173
            |||||..|||:..:|.:||.|||...
Frog   819 HRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGNHARQDSMEPSELWDDVSNCRCGDR 883

  Fly   174 ------------IKCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYFN 226
                        .:|.|:|.||||.::||||:|...   |....|.||:|:...|:...:||:..
Frog   884 LKTLEQRAKRQHHRCLAHSLVGTPNYIAPEVLLRKG---YTQLCDWWSVGVILFEMLVGQPPFLA 945

  Fly   227 MN 228
            .|
Frog   946 SN 947

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	62/261 (24%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	62/259 (24%)
lats2	XP_012811721.1	UBA_LATS2	102..142	CDD:270581
lats2	XP_012811721.1	PKc_like	696..1075	CDD:419665	62/261 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910