DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment car and ATVPS33

DIOPT Version :9

Sequence 1:	NP_001259707.1	Gene:	car / 32947	FlyBaseID:	FBgn0000257	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001154679.1	Gene:	ATVPS33 / 824651	AraportID:	AT3G54860	Length:	608	Species:	Arabidopsis thaliana

Alignment Length:	634	Identity:	197/634 - (31%)
Similarity:	337/634 - (53%)	Gaps:	63/634 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VNLQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLLALKPELHLPRE 76
            :||:.:::.:.|||:..|..:.|:|.:|:|..:.|.:.|:.......:.|:.|..|..| .:..|
plant    12 LNLKSIRDKSERELVNLLKDVRGTKCLVIDPKLSGSVSLIIPTSKLKELGLELRHLTAE-PVQTE 75

  Fly    77 VANVVYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNIEEL 141
            ...|||::|.:::.|:.:|:|::.....|..|.|::.|.||||..|...||...| .:...::|.
plant    76 CTKVVYLVRSQLSFMKFIASHIQNDIAKAIQRDYYVYFVPRRSVACEKILEQEKV-HNLVTVKEF 139

  Fly   142 AWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGEFAHRVWEH 206
            ....:|||.|::|.|:..:.:|..||||.|||:..|..:.:|:..:|.|.|:..||:.:.||.:.
plant   140 PLYMVPLDEDVISFELELSEKDCLVDGDVSSLWHIAKAIHELEFSFGVISKMRAKGKASVRVADI 204

  Fly   207 AKQLGRDERTLYNGDKG--VVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLPAENF 269
            ..:: :.|..:.:.|.|  .||.||||||.:|:::|:.:||||||||||...|
plant   205 LNRM-QVEEPVNSNDVGRPEVDTLILLDREVDMVTPMCSQLTYEGLIDEILHI------------ 256

  Fly   270 PSDGALPGGGGSGPRVEESQSLLG---DTEKKTILLHS----------------GEQLYAELRNK 315
             |:||          ||...|::|   :.:|..:.|:|                .::|:.|.|:.
plant   257 -SNGA----------VEVDSSVMGAQQEGKKMKVPLNSSKYDAWNIYFDFRGLDNDKLFKETRDL 310

  Fly   316 HFNEVTKLLARKA---REIHVQMHATSQDKSVQEIKSFVE--NLLPQLMAQKKATSEHTAIAGLL 375
            :|..|.::|.:||   :|.:.::::|   ::|.|:|.||:  |.||::       :.|..:|..|
plant   311 NFEVVVQVLRQKAMTMKEDYTEINST---QTVSELKDFVKKLNSLPEM-------TRHIHLAQHL 365

  Fly   376 HEQVNAVRFADDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLN 440
            ....:...|...|..||..:...:.|....|||::|..:..|..||||:.:.....||..:|..:
plant   366 TTFTSKQSFNSQLDMEQTLVEAENYDICYEYIEEMIHKQEPLTNVLRLLVLFSVTNSGLPKKQFD 430

  Fly   441 HYKRELVHVYGLEVLLTISNLEKSGLLHLQTESRAYSVLRKTLHLTVDDNVEIEPKDISYVHSFY 505
            :.:.||:|.||.|.::|::||||:|||..|.....:..:::||.|.|:|.....|.||:||:|.|
plant   431 YIRMELLHSYGFEHVVTLNNLEKAGLLKKQEFKSNWLTVKRTLKLIVEDTDTSRPNDIAYVYSGY 495

  Fly   506 APLTARIVEHSLKPLGWQTLKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLV 570
            |||:.|:::.::.. ||:.::..:..||||..|..::.........::...|.|.......:|||
plant   496 APLSIRLIQQAIHS-GWRPMEDILKLLPGPHLETKRSGFPSSPSVDSLHGASNGVADGRRSIVLV 559

  Fly   571 CFVGGCTFAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMSSXG 619
            .|:||.|||||:|||:||::|....:.::||||:||..:.:::.|...|
plant   560 VFIGGVTFAEISALRYLASKEGMAYDLIVATTKIVNGATLIETFMEKLG 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	186/595 (31%)
ATVPS33	NP_001154679.1	Sec1	36..596	CDD:279352	187/596 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	273	1.000	Domainoid score	I429
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11294
Inparanoid	1	1.050	289	1.000	Inparanoid score	I838
OMA	1	1.010	-	-		QHG53951
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	1	1.000	-	-		FOG0002117
OrthoInspector	1	1.000	-	-		oto2897
orthoMCL	1	0.900	-	-		OOG6_101460
Panther	1	1.100	-	-	O	PTHR11679
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840