Protein Alignment car and vps45

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001072504.1
• Gene: vps45 / 779959
• XenbaseID: XB-GENE-961682
• Length: 570
• Species: Xenopus tropicalis
• Alignment Length: 625
• Identity: 131/625 - (20%)
• Similarity: 230/625 - (36%)
• Gaps: 149/625 - (23%)

  Fly    55 KLFADR--GIRLLALKPELHLPREVANVVY----VMRPRVALMEQLAA-------HVKA--GGRA 104
            |:..|.  |:::|.:..|   ...|.::||    :::..|.|.|::.:       |:||  ..|.
 Frog    13 KMIEDSGPGMKVLLMDKE---TTSVVSMVYTQSEILQKEVYLFERIDSTNRESMKHLKAICFLRP 74

  Fly   105 AAGRQYHILFAPRRSCLCVSQLEVSGVLGS--------------FGNIEELAWNYLPLDVDLVSM 155
            ......:::...||....|..|..|.|:..              ...::|...:|:.::..:.|:
 Frog    75 TKENVEYLIKELRRPKYSVYFLYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHVFSL 139

  Fly   156 EMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGK--GEFAHRVWEHAKQLGRDERTLY 218
            .:...::  ..:.|...||:...||..|.....:.|.|..:  .:.|.|:.|..||:...|..|:
 Frog   140 NIVGCYQ--GRNWDAVHLYRTTQGLTALLLSLKKCPMIRYQLSSDMAKRLAEGVKQVITKEYELF 202

  Fly   219 NGDKGVVDQLIL-LDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLPAENFPSDGALPGGGGSG 282
            ...:..|..|:| ||||.|.::||..|.||:.::.|..||..|::.|        ..:||
 Frog   203 EFRRTEVPPLLLILDRSDDAITPLLNQWTYQAMVHEMLGINNNRIDL--------SRVPG----- 254

  Fly   283 PRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKAREIHVQMHATSQD-KSVQE 346
                     :....|:.:|....::.||.....:|.|:...:.....:...:.....|. :|:.:
 Frog   255 ---------ISKDLKEVVLSAENDEFYANNMYLNFGEIGTNIKNLMEDFQKKKPKGQQKLESISD 310

  Fly   347 IKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAAEQEFMVCADIDKPSAYIEDLI 411
            :|:|||| .||........|:|..:.|.|..          |.:|:..|..::       :|..:
 Frog   311 MKAFVEN-YPQFKKMSGTVSKHVTVVGELSR----------LVSERHLMEVSE-------VEQEL 357

  Fly   412 ACRVE----LNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLLTISNLEKSGLLHLQTE 472
            ||:.:    |..|.||:..|         :|.......||.:|.|......||    .|..|..:
 Frog   358 ACQNDHSNALQNVKRLLQNQ---------RLAELDATRLVMLYALHYERHSSN----ALSSLLND 409

  Fly   473 SRAYSVLRKTLHLTVDDNVE-----------IEPKD--------------ISYVHSFYAPLTARI 512
            .|...|..|...| |...||           ..|||              :..|::.:.|.....
 Frog   410 LRVRGVSEKYRRL-VSAVVEYGGKRVRGSDLFSPKDAVAITKQFFKGLKGVENVYTQHQPFLLDT 473

  Fly   513 VEHSLKPLGWQTLKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLVCFVGGCT 577
            ::..:|    ..||..:....||                       .:|.:.|:.::|..|||.|
 Frog   474 LDQLIK----GKLKDNLYPYLGP-----------------------NTLRDRPQDIIVFMVGGAT 511

  Fly   578 FAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMSS 617
            :.|..|: :...:....|..::..|.:.|..|||:.:.|:
 Frog   512 YEEAFAV-YNLNRTTPGVRIVLGGTAIHNTKSFLEEVQSA 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	126/612 (21%)
vps45	NP_001072504.1	Sec1	23..539	CDD:279352	123/602 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910