Protein Alignment car and Vps33b

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_071622.1
• Gene: Vps33b / 64060
• RGDID: 620644
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 652
• Identity: 180/652 - (27%)
• Similarity: 306/652 - (46%)
• Gaps: 81/652 - (12%)

  Fly     2 FPHLKGHGQRVNLQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGI-RLL 65
            |||.....:..:..:|:..|..:|:..|:::.|.|.:.::..::.|||.:....:.....: :|.
  Rat     3 FPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLY 67

  Fly    66 ALKPELHLPREVANVVYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEVSG 130
            .::.:|.|... ..:.:::|||:..|..:|..|.|...|...|:|.|:.:|::...|...||..|
  Rat    68 KVENKLTLSSN-EQLCFLVRPRIKTMRYIANLVNADKLAGRVRKYKIILSPQKFYACEMVLEEEG 131

  Fly   131 VLGSFGNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYG 195
            |.|.. :.:|.|::.|||||||:|||:|..|||..::||...:...|..|..|..|||..|..||
  Rat   132 VYGDV-SCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYG 195

  Fly   196 KGEFAHRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQN 260
            .|......::..::|..:|.:...|.:..:..:.||||.:|.::.|.:|:.||||:|:.:.|:
  Rat   196 IGRCTKMSYDLWRKLEEEEDSETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIK-- 258

  Fly   261 KLTLPAENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLA 325
                           .|....||.|..|...|      .:||::.:::::|:||:||:.|...|:
  Rat   259 ---------------CGSVDFGPEVTSSDKSL------KVLLNAEDKVFSEIRNEHFSNVFGFLS 302

  Fly   326 RKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAA 390
            :|||.:..| :...:...::::|:||...|..|..:.:..|.|......:.::.....|.:.:..
  Rat   303 QKARNLQAQ-YDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKT 366

  Fly   391 EQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVL 455
            |...:...:|.:.::|||:.|..:|.....|||:|:.....:|...|.....|.:.:..||.|.|
  Rat   367 EHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHL 431

  Fly   456 LTISNLEKSGLL-----------------HLQTESRA---------------YSVLRKTLHL--T 486
            ||.|||.::|||                 .|.|:..|               :..:.|.|:|  .
  Rat   432 LTFSNLRRAGLLTEQASGDTLTAVENKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPR 496

  Fly   487 VDDNVEIE-PKDISYVHS-FYAPLTARIVEHSLKPLGWQTLKSQIN--NLPGPTFEDFQAQLVGI 547
            ||...::: |:|::||.| .|.||:.||:|..|....||.|...:.  |.....|.|...:
  Rat   497 VDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLDRRSWQGLDEVVRLLNCSDFAFTDMAKE---- 557

  Fly   548 GGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLD 612
                  ...|..||    |::||.|:|||||:||:|||||.  .:....|:..||.|.|....::
  Rat   558 ------DKASSESL----RLILVVFLGGCTFSEISALRFLG--REKGYRFIFLTTAVTNSARLME 610

  Fly   613 SL 614
            ::
  Rat   611 AM 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	171/608 (28%)
Vps33b	NP_071622.1	Sec1	37..405	CDD:279352	107/393 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53951
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	1	1.000	-	-		FOG0002117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1571
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830