Protein Alignment car and stxbp1a

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_005161170.1
• Gene: stxbp1a / 574003
• ZFINID: ZDB-GENE-050626-106
• Length: 603
• Species: Danio rerio
• Alignment Length: 637
• Identity: 125/637 - (19%)
• Similarity: 240/637 - (37%)
• Gaps: 85/637 - (13%)

  Fly    19 EAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLLALKPELHLPREVANVVYV 83
            |....::::::.:....|.:::|:..:..|....:.......||.::....:...|......:|:
Zfish    12 EKIMNDVIKKVKKKGEWKALIVDQLSMRMLSSCCKMTDIMTEGITIVEDIMKRREPLPSLEAIYL 76

  Fly    84 MRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNIEELAWNYLPL 148
            :.|....::.|....| ...:|..:..|:.|.........:::..|....:...:.|:...:||.
Zfish    77 ITPTDKSVQTLINDFK-DPHSAKYKGAHVFFTDSCPDPLFNEVVKSRASKTIKTLNEINIAFLPY 140

  Fly   149 DVDLVSMEMPNAFRDVSVDGDTS----SLYQAAVGLVQLQRLYGRIPKIYGKGEF------AHRV 203
            :..:.|::.|:||:.......|.    .:.:.|..|..|.......|.:..:||:      |..:
Zfish   141 ESQVFSLDNPDAFQSFYSPHKTQLKNPVMERLAEQLATLCATLKEYPAVRYRGEYKDNATLAQLL 205

  Fly   204 WEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLPAEN 268
            .:.......|:.|:..|......|||:|||..|.:||:..:||::.:..:.         ||.||
Zfish   206 QDKLDAYKADDPTMGEGPDKARSQLIILDRGFDPVSPVLHELTFQAMAYDL---------LPIEN 261

  Fly   269 ----FPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKAR 329
                :.:.|                  :||:.:|.:|||..:.|:..||:||..||::.:.|..:
Zfish   262 DVYKYDTSG------------------IGDSREKEVLLHEDDDLWVALRHKHIAEVSQEVTRSLK 308

  Fly   330 EIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAG--LLHEQVNA---VRFADDLA 389
            |........:.:|:.....|.:...:||...:....|.|..:|.  :.|.|...   .|...|||
Zfish   309 EFSASKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLQLAEDCMKHYQGTVDKLCRVEQDLA 373

  Fly   390 ----AEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKE----KLLNHYKREL 446
                ||.|.:.    |...|.:..|:...|.....:|:|.:.....:|..|    ||:.|.:
Zfish   374 MGTDAEGEKIK----DPMRAIVPILLDANVTTYDKIRIILLYIFLKNGITEENLNKLIQHAQ--- 431

  Fly   447 VHVYGLEVLLTISNLEKSGLLHLQTESRAYSVLRKTLHLTVDDNVEIEPKDISYVHSFYAPLTAR 511
            :.....|::        :.:.||.......|.||:...:...:.|    .:.:|..|.:.||...
Zfish   432 IPPEDSEII--------TNMAHLGVPIITDSTLRRGKKMDRKERV----SEQTYQLSRWTPLIKD 484

  Fly   512 IVEHSLKPLGWQTLKSQINNLP---GPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLVCFV 573
            |:|.::..      |....:.|   ..:...|....|.....|.....:.|.....|| ::|..:
Zfish   485 IMEDAIDD------KLDTKHYPYISTRSSSSFSTSAVSARYGHWHKNKTPGEYRTGPR-IMVFII 542

  Fly   574 GGCTFAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMSSXGRRLSRL 625
            ||.:|:|:.. .:...|.:...|.::.:|..:....||..|... .|..:|:
Zfish   543 GGASFSEMRC-AYEVTQANGKWEAIVGSTHSLTPTKFLMDLRHPDFRESTRV 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	119/599 (20%)
stxbp1a	XP_005161170.1	Sec1	29..575	CDD:279352	119/600 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810