Protein Alignment car and vps45

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001243585.1
• Gene: vps45 / 561653
• ZFINID: ZDB-GENE-060503-526
• Length: 568
• Species: Danio rerio
• Alignment Length: 631
• Identity: 131/631 - (20%)
• Similarity: 244/631 - (38%)
• Gaps: 151/631 - (23%)

  Fly    61 GIRLLALKPELHLPREVANVVY----VMRPRVALMEQLAA-------HVKA--GGRAAAGRQYHI 112
            |:::|.:..|   ...:.:|||    :::..|.|.|::.:       |:||  ..|.......|:
Zfish    21 GMKVLLMDKE---TTSIVSVVYTQSEILQKEVYLFERIDSQNRDNMKHLKAICFLRPTKENVEHL 82

  Fly   113 LFAPRRSCLCVSQLEVSGVLGS--------------FGNIEELAWNYLPLDVDLVSMEMPNAFRD 163
            :...||....|..:..|.|:..              ...::|...:::.::..|.|:.:....|.
Zfish    83 IQELRRPKYSVYFIYFSNVISKSEVKALAEADEQEVVAEVQEFYGDFIAVNPHLFSLNLQGVSRG 147

  Fly   164 VSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGK--GEFAHRVWEHAKQLGRDERTLYNGDKGVVD 226
            .|  .:.|.|.:...||..:.....:.|.|..:  .:.:.|:.|..||:...|..|::..|..|.
Zfish   148 RS--WEPSVLPRVTQGLTSVLLSLKKCPMIRYQLSSDMSKRLAESVKQIITKEYELFDFRKTEVP 210

  Fly   227 QLIL-LDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLPAENFPSDGALPGGGGSGPRVEESQS 290
            .|:| ||||.|.::||..|.||:.::.|..|:..|::.|        ..:||
Zfish   211 PLLLILDRSDDAITPLLNQWTYQAMVHELLGLNNNRIDL--------SRVPG------------- 254

  Fly   291 LLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKAREIHVQMHATSQD-KSVQEIKSFVENL 354
             :....::.:|....::.||.....:|.|:...:.....:...:.....|. :|:.::|:||||
Zfish   255 -ISKDLREVVLSAENDEFYANNLYLNFGEIGTNIKNLMEDFQKKKPKDQQKLESISDMKAFVEN- 317

  Fly   355 LPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAAEQEFMVCADIDKPSAYIEDLIACRVELNR 419
            .||........|:|..:.|.|..          |.:|::.|..:::::..|...|....:..|.|
Zfish   318 YPQFKKMSGTVSKHVTVVGELSR----------LVSERQLMEVSEVEQELACQNDHSNAQQMLRR 372

  Fly   420 VL-----------RLICM-----QCHAAS---GFKEKL----LNHYKRELVHV---YGLEVLLTI 458
            :|           ||:.:     :.|::|   ...|:|    ::...|::||.   ||.:
Zfish   373 LLQSPRLSEIDAVRLVMLYALRYEKHSSSILPSLMEELNRKGVSERHRKMVHAVVEYGGK----- 432

  Fly   459 SNLEKSGLLHLQTESRAYSVLRKTLHLTVDDNVEIEPKDISYVHSFYAPLTARIVEHSLKPLGWQ 523
             .:..|.|:   |.:.|.|:.::..            |.:..|.:.|       .:|  :||...
Zfish   433 -RIRGSDLI---TPTDAVSITKQFF------------KGLKGVENVY-------TQH--QPLLHD 472

  Fly   524 TLKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLA 588
            ||...|..    ..:|.|...:|           ..||.:.|:.::|..:||.|:.| |...:..
Zfish   473 TLDQLIKG----RLKDSQFPYLG-----------PSSLRDRPQDIIVFIIGGATYEE-ALTVYNL 521

  Fly   589 AQEDNNVEFLIATTKVVNKHSFLDSLMSS----------XGRRLSR 624
            .:....|..::..|.:.|..|||:.:|.|           ||::||
Zfish   522 NRTMPGVRIVLGGTHIHNTKSFLEEVMLSVGSGGDRSQIGGRQMSR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	121/601 (20%)
vps45	NP_001243585.1	Sec1	23..539	CDD:279352	120/599 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810