Protein Alignment car and vps33a

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_012818531.1
• Gene: vps33a / 549689
• XenbaseID: XB-GENE-978483
• Length: 614
• Species: Xenopus tropicalis
• Alignment Length: 611
• Identity: 269/611 - (44%)
• Similarity: 382/611 - (62%)
• Gaps: 32/611 - (5%)

  Fly    11 RVNLQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGI-RLLALKPELHLP 74
            ||||.:|:||...||.:.||:..|||.||.||.:.||..|:.:..|..:..: ::..||......
 Frog    22 RVNLNILREAMRMELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKSGPLPS 86

  Fly    75 REVANVVYVMRPRVALMEQLAAHVKAGGRAA-AGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNI 138
            .:|.|:::.:|||:.||:.:|.:::...|.. ..|.::|||.||||.||..:|:..||||||.:.
 Frog    87 SDVKNIIFFVRPRLELMDIIADNIQREERGRFPQRDFYILFVPRRSILCEQRLKDLGVLGSFMHR 151

  Fly   139 EELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGEFAHRV 203
            :|...|.:|.|.||:|||..|||::..::.|.:||||||.||..||.|||.||:|.||||.|..|
 Frog   152 DEYRLNLIPFDGDLLSMESENAFKECYLENDQTSLYQAAKGLTTLQSLYGTIPQICGKGECARHV 216

  Fly   204 WEHAKQLGRDERTL---YNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLP 265
               |..:.|.:|.|   .|....|.|.|:||||::|||:||||||||||||||.|||:.:.:.||
 Frog   217 ---ANMMIRMKRELGGSQNQITPVFDTLLLLDRNVDLLTPLATQLTYEGLIDEVYGIQNSHVKLP 278

  Fly   266 AENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKARE 330
            .|.|     .|...|.|     .:.|  .||.|.:||:|.|:||||:|:|:||.|..:|::||:.
 Frog   279 PEKF-----APKKQGEG-----GKDL--PTEPKKLLLNSAEELYAEIRDKNFNAVGSVLSKKAKI 331

  Fly   331 IHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAAEQEFM 395
            |..........|:|.|||.||.. ||.:.|:|.:.:.||:||.|:.|...:..|.|:|..|||||
 Frog   332 ISAAFEGRHNAKTVGEIKQFVSQ-LPHMQAEKASLANHTSIAELIKEITTSEAFFDNLTVEQEFM 395

  Fly   396 VCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLLTISN 460
            ...|.||.:.||||.||.:..:.::|||:|:|....:|.|:|:|::||||::..||.|.:||:.|
 Frog   396 SGFDTDKVNPYIEDCIAKKDPIIKILRLVCLQSVCNTGLKQKVLDYYKREILQTYGYEHILTLHN 460

  Fly   461 LEKSGLLHLQTESR-AYSVLRKTLHLTVDDNVEIEPKDISYVHSFYAPLTARIVEHSLKPLGWQT 524
            |||:|||.||..|| :|..:||||.|.:||..|..|.|||||:|.||||:.|:.:..::| ||::
 Frog   461 LEKAGLLKLQASSRNSYPTIRKTLRLWMDDVNEQNPNDISYVYSGYAPLSVRLAQILVRP-GWRS 524

  Fly   525 LKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAA 589
            ::..:..||||.||:.|:...|:     :....:|.    .:|:||.|:||.|||||||||||:.
 Frog   525 IEEVLKILPGPQFEERQSLPPGL-----LKKRQQGE----NKVILVFFLGGVTFAEIAALRFLSQ 580

  Fly   590 QEDNNVEFLIATTKVVNKHSFLDSLM 615
            .||...|::|||||:::..:::.|||
 Frog   581 MEDGGTEYIIATTKLISGTTWIKSLM 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	253/575 (44%)
vps33a	XP_012818531.1	Sec1	47..598	CDD:366407	253/576 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	425	1.000	Domainoid score	I615
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H11294
Inparanoid	1	1.050	449	1.000	Inparanoid score	I1580
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	1	1.000	-	-		FOG0002117
OrthoInspector	1	1.000	-	-		oto102992
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060