Protein Alignment car and Scfd1

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_062237.1
• Gene: Scfd1 / 54350
• RGDID: 619828
• Length: 637
• Species: Rattus norvegicus
• Alignment Length: 720
• Identity: 145/720 - (20%)
• Similarity: 270/720 - (37%)
• Gaps: 190/720 - (26%)

  Fly     7 GHGQRVNLQLLQEAACRELLQ-QLDRIEGS------KVIVLD---ETMIGPLDLVTRPKLFADRG 61
            |.....:::..|..|.:.:|. .:..::.|      ||::.|   :.:|.||..|   |...|.|
  Rat     3 GSKMAASIRERQTVALKRMLNFNVPHVKNSPGEPVWKVLIYDRFGQDIISPLLSV---KELRDMG 64

  Fly    62 IRLLALKPELHLPRE-VANV--VYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCV 123
            |.|..|   ||..|: :.:|  ||.:.|....:::|...:    |......|::.|.   |.:..
  Rat    65 ITLHLL---LHSDRDPIRDVPAVYFVMPTEENIDRLCQDL----RNQLYESYYLNFI---SAISR 119

  Fly   124 SQLE-------VSGVLGSFGNIEELAWNYLPLDVDLVSMEMPN----AFRDVS------------ 165
            |:||       .:..:.....:.:...|::.|:.|:..:...|    ::|.::
  Rat   120 SKLEDIANAALAANAVTQVAKVFDQYLNFITLEEDMFVLCNQNKELVSYRAINRPDITDTEMETV 184

  Fly   166 VDGDTSSLYQAAVGLVQLQRLYGRIPKI-YGKGEFAHRVWEHAKQLG-------RDER-TLYNGD 221
            :|....||:...|.|       |.:|.| ..:|..|..|   |.:|.       ||.| :|:.||
  Rat   185 MDTIVDSLFCFFVTL-------GAVPIIRCSRGTAAEMV---AVKLDKKLRENLRDARNSLFTGD 239

  Fly   222 KGVVDQ-------LILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLP----AENFPSDGAL 275
            .....|       |:|:||:|||.:||....||:.|:.:......|::.|.    .||.|:
  Rat   240 PLGTGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPT---- 300

  Fly   276 PGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKAREIHVQMHATSQ 340
                |:.|:.:         .||:..|...::.:.:.:...|.||.:.:.::......|.....:
  Rat   301 ----GARPKRK---------NKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKR 352

  Fly   341 DKSVQEIKSFVE-----------------NLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDL 388
            .||:..::...|                 :.||:|:.:|:....||.:|..:.|.:.|.:.....
  Rat   353 LKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYF 417

  Fly   389 AAEQEFMVCADIDKPSAYIEDLIA---CRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVY 450
            ..|::.|....:||.   :.|:|:   .....:::...:.....|.....|..|..||:
  Rat   418 EYEEKIMSKTTLDKS---LLDVISDPDAGTPEDKMRLFLIYYISAQQAPSEVDLEQYKK------ 473

  Fly   451 GLEVLLTISNLEKSGLLHLQTESRAYSVLRKTLHLTVDDNVEIEPKDISYVHSFYAP--LTARI- 512
                .||.:....|.|.::: :.:|::.:..|              ..||.::...|  |.:|:
  Rat   474 ----ALTDAGCNLSPLQYIK-QWKAFAKMAST--------------PASYGNTTTKPMGLLSRVM 519

  Fly   513 ------VEHSLKPLGWQTLKSQINNLP-------------GPTFEDFQAQLVGIGGRHTVTTVSE 558
                  |...:|.|   .||.|  |||             .|..:|:         |:....:..
  Rat   520 NTGSQFVMEGVKNL---VLKQQ--NLPVTRILDNLMEMKSNPETDDY---------RYFDPKMLR 570

  Fly   559 GSLLNVPR------VVLVCFVGGCTFAEIAAL-RFLAAQEDNNVEFLIATTKVVNKHSFLDSLMS 616
            .:..:|||      ..:|..|||..:.|...| .::..::..::  |...:::.|...|:..| |
  Rat   571 SNDSSVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKGKQGKHI--LYGCSEIFNATQFIKQL-S 632

  Fly   617 SXGRR 621
            . |::
  Rat   633 QLGQK 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	135/667 (20%)
Scfd1	NP_062237.1	Sec1	39..457	CDD:279352	97/460 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810