Protein Alignment car and vps33b

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001014370.1
• Gene: vps33b / 541534
• ZFINID: ZDB-GENE-050327-73
• Length: 617
• Species: Danio rerio
• Alignment Length: 651
• Identity: 178/651 - (27%)
• Similarity: 314/651 - (48%)
• Gaps: 99/651 - (15%)

  Fly    13 NLQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLL---ALKPELHLP 74
            :..||:..|..:|:..|:::.|.|.:.:|..::.|||.:....:.....:..|   .|||   :.
Zfish    14 DFSLLKRLARDQLIFLLEQLPGKKDLFIDADLMSPLDRIANVTILKQHEVDKLYKVELKP---IV 75

  Fly    75 REVANVVYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNIE 139
            .....:.:::|||:..::.::..|.:...|...|:|.|:|.|::...|.:.||..||   :|::.
Zfish    76 SSSDQLCFLIRPRIQTVKWISDLVNSDKVAGRFRRYKIIFTPQKFYACETVLEEQGV---YGDVT 137

  Fly   140 ELAWNY--LPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGEFAHR 202
            ...||:  ||||.|::|:|:|..|||..::||...:......|..||.:||...|:||.|..|..
Zfish   138 TDEWNFYILPLDDDILSLELPEFFRDNFLEGDQRWVTTGGGALHLLQSVYGSFSKVYGIGRCAKM 202

  Fly   203 VWEHAKQLGR--DERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLP 265
            |:|..::|..  ::||    .:....::.|:||.:|.::||.:|:.||||:|:.:.|:.:.:..
Zfish   203 VYESWRELMEEGEQRT----RQPEFAKVFLIDRDVDFVTPLCSQVVYEGLVDDIFRIKCSSVEF- 262

  Fly   266 AENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKARE 330
                            ||.|..|...:      .::|:|.::::.|:||:||:.|...|::||:.
Zfish   263 ----------------GPDVTSSDKSI------KVMLNSQDKVFNEIRNEHFSNVFGFLSQKAKN 305

  Fly   331 IHVQMHATSQDK----SVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAAE 391
            :.     |:.||    .:|::|:||.:.|..|..:.:..|.|...:..:.::.....|.:.|..|
Zfish   306 LQ-----TAYDKRRGMDIQQMKAFVADELKGLKQEHRLLSLHIGASESIMKKKTKQDFQELLKTE 365

  Fly   392 QEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLL 456
            ...:...:|.:..||||:.|..:|.:...|||:|:.....:|...|.....|.:.:..||:|.||
Zfish   366 HSLLEGFEIRECIAYIEEHINRQVSMIDSLRLLCLLSITENGLLSKDYRSLKAQYLQSYGIEHLL 430

  Fly   457 TISNLEKSGLLHLQ--------TESRA------------------------YSVLRKTLHLTVDD 489
            |.:||.:.|||..|        .||:.                        :..|.|.|.|....
Zfish   431 TFANLRQLGLLEEQQTGETLTVMESKVGKLVNDKTAGKLTDAFSSLAKKSNFRALSKRLALVPKS 495

  Fly   490 NVEIE---PKDISYVHS-FYAPLTARIVEHSLKPLGWQTLKSQINNLPGPTFEDFQAQLVGIGGR 550
            ..|.:   |:|::|:.| .|.||:.:::|..|:..||..|:.....|.|   :||..    .||
Zfish   496 GEEYDLRVPRDMAYIFSGAYIPLSCKLIEQVLERDGWTGLEEVTRMLNG---QDFAV----TGG- 552

  Fly   551 HTVTTVSEG-SLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSL 614
               ::.||. :..|..|::||.|:||||::||:|||||.  ::....|::.||.:.|....|::|
Zfish   553 ---SSSSEARNKSNGQRIILVMFLGGCTYSEISALRFLG--KERGCRFIVLTTAITNSGRLLEAL 612

  Fly   615 M 615
            :
Zfish   613 L 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	169/617 (27%)
vps33b	NP_001014370.1	Sec1	37..605	CDD:279352	169/618 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53951
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	1	1.000	-	-		FOG0002117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830