Protein Alignment car and Vps33B

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_651395.1
• Gene: Vps33B / 43077
• FlyBaseID: FBgn0039335
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 663
• Identity: 150/663 - (22%)
• Similarity: 264/663 - (39%)
• Gaps: 102/663 - (15%)

  Fly    14 LQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGI-RLLALKPELHLPREV 77
            ||..|..|..:|...|..|.|.|.::|:..:|.||:.|........:|| |:........|||..
  Fly     9 LQGFQLVAQEKLCSILCSIPGKKELILEPDLIKPLEHVVTASWLKLKGIQRIYKHDAAQSLPRSA 73

  Fly    78 ANV-VYVMRPRV----ALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQ--LEVSGVLGSF 135
            ..| :|::|..:    .|::||...........:.:.|||:..|  ||....|  ||.:|:.| .
  Fly    74 DQVHIYMIRSVLGTFQTLLKQLQPVASEEMPDISMKMYHIVCVP--SCYSYFQTLLEQAGLYG-L 135

  Fly   136 GNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGEFA 200
            ..:....|:::..|..::|:|:||.:..:.:..:||.|...|..|..||.:.|:...|...|..:
  Fly   136 VQLHHFNWDFIYFDQGVLSLELPNLYECLYLQKNTSPLPAVAQSLRLLQMICGQPSLILSFGHHS 200

  Fly   201 HRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLP 265
            .::.:.||.||:........|.|   ..:::||..|..:.|.|...|.||:.|.:
  Fly   201 SQLMQMAKTLGKLPAPTNPPDYG---GWLVIDRDKDYPASLLTPAIYAGLLLEVF---------- 252

  Fly   266 AENFPSDGALPGGGGSGPRVEESQSLLGDTEK---------KTILLHS-GEQLYAELRNKHFNEV 320
              ...|...|.....:..|.:..:.|.|...|         .:|.|:| .:::|.:.|.|.|.:|
  Fly   253 --EHSSGEILVDNSKNKIRSQRVELLQGKKSKIGVNSASKPCSIRLNSTSDEIYGDNRYKRFAQV 315

  Fly   321 TKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFA 385
            :.|:..:.:.:.:::...: |..:.|:..:|...||:|...|.....|...:.::.:.:...|..
  Fly   316 SSLIHAQVKALGLELQKLN-DMQLDEMHDYVARKLPKLTELKSKVLRHLNASEIVIQMMGNFRKL 379

  Fly   386 DDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVY 450
            ..|  |::.:......:..:.|::|:....:....|||:|: .|...|...:.|..:.|...:::
  Fly   380 QTL--EEDILNNDSRKRLLSEIDELLTTDGQRFNTLRLLCL-LHHCVGVAPEELQIFARNYCNLF 441

  Fly   451 GLEVLLTISNLEKSGLL-HLQTESRAYSVLRKTLHLTVDDNVEI--------------------- 493
            |.:.|.....|.::||| .|..|.:|.:.|...|.|......|.
  Fly   442 GHQELGVFQQLSQAGLLPPLVVEKKAPTKLLSNLPLPKFQQTEFQANANRLKLLTSSGDGQDGGS 506

  Fly   494 ----EPKDISYVHSF-----YAPLTARIVEHSLKPLGWQTLKSQINNLPG-----------PTFE 538
                :...:....||     |.||.|::....||....:.|.|::..:.|           |...
  Fly   507 SSKSQSSGLQTCPSFVFNGTYIPLVAQLCSILLKINSAEELSSKLGMIEGLHLHLDSGKITPKAY 571

  Fly   539 DFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIATTK 603
            ..|.:|.|:..:....       |.: |.:.|..|||.::|||||..|:|  :....:..:|:
  Fly   572 ASQVKLNGVADQDMFP-------LRL-RNLFVFIVGGASYAEIAACDFVA--KLTGAQITVAS-- 624

  Fly   604 VVNKHSFLDSLMS 616
                    ||||:
  Fly   625 --------DSLMA 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	138/629 (22%)
Vps33B	NP_651395.1	Sec1	31..406	CDD:279352	88/395 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464242
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3097
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11679
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800