Protein Alignment car and Stxbp1

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_006234001.1
• Gene: Stxbp1 / 25558
• RGDID: 3785
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 657
• Identity: 129/657 - (19%)
• Similarity: 240/657 - (36%)
• Gaps: 125/657 - (19%)

  Fly    19 EAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLLALKPELHLPREVANVVYV 83
            |....::::::.:....||:|:|:..:..|....:.......||.::....:...|......||:
  Rat    12 EKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPSLEAVYL 76

  Fly    84 MRPRVALMEQLAAHVK----AGGRAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNIEELAWN 144
            :.|....:..|.:..|    |..|||     |:.|.........::|..|........:.|:...
  Rat    77 ITPSEKSVHSLISDFKDPPTAKYRAA-----HVFFTDSCPDALFNELVKSRAAKVIKTLTEINIA 136

  Fly   145 YLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRI----------PKIYGKGEF 199
            :||.:..:.|::..::|:..      .|.::|.:....|:||..:|          |.:..:||:
  Rat   137 FLPYESQVYSLDSADSFQSF------YSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEY 195

  Fly   200 ------AHRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIR 258
                  |..:.:.......|:.|:..|......||::|||..|..||:..:||::.:..:.
  Rat   196 KDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDL---- 256

  Fly   259 QNKLTLPAEN----FPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNE 319
                 ||.||    :.:.|                  :|:...|.:||...:.|:..||:||..|
  Rat   257 -----LPIENDVYKYETSG------------------IGEARVKEVLLDEDDDLWIALRHKHIAE 298

  Fly   320 VTKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQ--KKATSEHTAIAGLLHEQVNA- 381
            |::.:.|..::........:.:|:.....|.:...:||...:  |.:|..|.|...:.|.|...
  Rat   299 VSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVD 363

  Fly   382 --VRFADDLA----AEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLN 440
              .|...|||    ||.|.:.    |...|.:..|:...|.....:|:|.:.....:|..|:.||
  Rat   364 KLCRVEQDLAMGTDAEGEKIK----DPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLN 424

  Fly   441 HYKRELVHVYGLEVLLTISNLEKSGLLHLQTESRAYSVLRKTLHLTV----DDNVEIEPK----- 496
                :|:.                   |.|.......::....||.|    |..:....|
  Rat   425 ----KLIQ-------------------HAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKE 466

  Fly   497 ---DISYVHSFYAPLTARIVEHSLKPLGWQTLKSQINNLPGP-----TFEDFQAQLVGIGGRHTV 553
               :.:|..|.:.|:...|:|        .|::.:::....|     :...|....|.....|..
  Rat   467 RISEQTYQLSRWTPIIKDIME--------DTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWH 523

  Fly   554 TTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMSSX 618
            ...:.|...:.||:: :..:||.:..|:.. .:...|.:...|.||.:|.::....||..|....
  Rat   524 KNKAPGEYRSGPRLI-IFILGGVSLNEMRC-AYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPD 586

  Fly   619 GRRLSRL 625
            .|..||:
  Rat   587 FRESSRV 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	122/619 (20%)
Stxbp1	XP_006234001.1	Sec1	29..575	CDD:395791	122/620 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810