Protein Alignment car and Vps33b

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_835171.2
• Gene: Vps33b / 233405
• MGIID: 2446237
• Length: 617
• Species: Mus musculus
• Alignment Length: 652
• Identity: 180/652 - (27%)
• Similarity: 305/652 - (46%)
• Gaps: 81/652 - (12%)

  Fly     2 FPHLKGHGQRVNLQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLL- 65
            |||.....:..:..:|:..|..:|:..|:::.|.|.:.::..::.|||.:....:.....:..|
Mouse     3 FPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLY 67

  Fly    66 --ALKPELHLPREVANVVYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEV 128
              ..||.|....::.   :::|||:..|..:|:.|.|...|...|:|.::.:|::...|...||.
Mouse    68 KVENKPALSANEQLC---FLVRPRIKNMRYIASLVNADKLAGRIRKYKVILSPQKFYACEMVLEE 129

  Fly   129 SGVLGSFGNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKI 193
            .||.|.. :.:|.|::.|||||||:|||:|..|||..::||...:...|..|..|..|||..|..
Mouse   130 EGVYGDV-SCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNC 193

  Fly   194 YGKGEFAHRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIR 258
            ||.|..|...::..::|..:|.:...|.|..:..:.||||.:|.::.|.:|:.||||:|:.:.|:
Mouse   194 YGIGRCAKMSYDLWRKLEEEEDSETKGRKPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIK 258

  Fly   259 QNKLTLPAENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKL 323
                             .|....||.|..|...|      .:||::.:::::|:||:||:.|...
Mouse   259 -----------------CGSVDFGPEVTSSDKSL------KVLLNAEDKVFSEIRNEHFSNVFGF 300

  Fly   324 LARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDL 388
            |::|||.:..| :...:...::::|:||...|..|..:.:..|.|......:.::.....|.:.:
Mouse   301 LSQKARNLQAQ-YDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELI 364

  Fly   389 AAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLE 453
            ..|...:...:|.:.::|||:.|..:|.....|||:|:.....:|...|.....|.:.:..||.|
Mouse   365 KTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPE 429

  Fly   454 VLLTISNLEKSGLL-----------------HLQTESRA---------------YSVLRKTLHL- 485
            .|||.|||.::|||                 .|.|:..|               :..:.|.|:|
Mouse   430 HLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLI 494

  Fly   486 -TVDDNVEIE-PKDISYVHS-FYAPLTARIVEHSLKPLGWQTLKSQINNLPGPTFEDFQAQLVGI 547
             .||...::: |:|::||.| .|.||:.||:|..|....||.|...:..|....|
Mouse   495 PRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLDRRSWQGLDEVVRLLNCSEF---------- 549

  Fly   548 GGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLD 612
              ..|.|...:.:.....|::||.|:|||||:||:|||||.  .:....|:..||.|.|....::
Mouse   550 --AFTDTAKEDKASSESLRLILVVFLGGCTFSEISALRFLG--REKGYRFIFLTTAVTNSARLME 610

  Fly   613 SL 614
            ::
Mouse   611 AM 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	171/608 (28%)
Vps33b	NP_835171.2	Sec1	37..605	CDD:279352	171/609 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53951
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	1	1.000	-	-		FOG0002117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.830