Protein Alignment car and Vps45

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_038869.1
• Gene: Vps45 / 22365
• MGIID: 891965
• Length: 570
• Species: Mus musculus
• Alignment Length: 642
• Identity: 134/642 - (20%)
• Similarity: 242/642 - (37%)
• Gaps: 128/642 - (19%)

  Fly    21 ACRELLQQL--DRIEGSKVIVLDETMIGPLDLV-TRPKLFADRGIRLLALKPELHL-------PR 75
            |.::.:.::  |...|.||:::|:...|.:.:| |:.::          |:.|::|       .|
Mouse     6 AVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEI----------LQKEVYLFERIDSQNR 60

  Fly    76 EV---ANVVYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSFGN 137
            |:   ...:..:||....:|.|...:    |......|.|.|:...|...|..|..:........
Mouse    61 EIMKHLKAICFLRPTKENVEYLIQEL----RRPKYSIYFIYFSNVISKSDVKSLAEADEQEVVAE 121

  Fly   138 IEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGK--GEFA 200
            ::|...:|:.::..|.|:.:....:  ..:.|.:.|.:...||..|.....:.|.|..:  .|.|
Mouse   122 VQEFYGDYIAVNPHLFSLNILGCCQ--GRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAA 184

  Fly   201 HRVWEHAKQLGRDERTLYNGDKGVVDQLIL-LDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTL 264
            .|:.|..||:...|..|:...:..|..|:| |||..|.::||..|.||:.::.|..||..|::.|
Mouse   185 KRLGECVKQVISKEYELFEFRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDL 249

  Fly   265 PAENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKAR 329
                    ..:||              :....::.:|....::.||.....:|.|:...:.....
Mouse   250 --------SRVPG--------------ISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLME 292

  Fly   330 EIHVQMHATSQD-KSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAAEQE 393
            :...:.....|. :|:.::|:|||| .||........|:|..:.|.|...|:.....:....|||
Mouse   293 DFQKKRPKEQQKLESIADMKAFVEN-YPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQE 356

  Fly   394 FMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLLTI 458
             :.|.: |..||           |..|.||:         ...|:.......||.:|.|......
Mouse   357 -LACQN-DHSSA-----------LQNVKRLL---------QNPKVTEFDAVRLVMLYALHYERHS 399

  Fly   459 SNLEKSGLLHLQTESRAYSVLRKTLHLTVD---------------DNVEIEP------KDISYVH 502
            ||.....::.|:::..| ...||.:...|:               |.|.|..      |.:..|:
Mouse   400 SNSLPGLIVDLRSKGVA-EKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVY 463

  Fly   503 SFYAPLTARIVEHSLKPLGWQTLKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRV 567
            :.:.|.....::|.:|    ..||..:....||:                       :|.:.|:.
Mouse   464 TQHQPFLHETLDHLIK----GRLKENLYPYLGPS-----------------------TLRDRPQD 501

  Fly   568 VLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMSSXGRRLSR 624
            ::|..:||.|:.| |...:...:....|..::..|.:.|..|||:.:::|.....||
Mouse   502 IIVFIIGGATYEE-ALTVYNLNRTTPGVRIVLGGTTIHNTKSFLEEVLASGLHSRSR 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	124/605 (20%)
Vps45	NP_038869.1	Sec1	23..539	CDD:279352	124/605 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810