Protein Alignment car and vps-45

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_741714.1
• Gene: vps-45 / 180449
• WormBaseID: WBGene00016643
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 638
• Identity: 126/638 - (19%)
• Similarity: 243/638 - (38%)
• Gaps: 143/638 - (22%)

  Fly    14 LQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKL---FADRGIRLLALKPELHLPR 75
            :.|:|.:  |:|:|.:.::.||::.:|      .:|..|.|.:   ||...:    ::.|:::..
 Worm     1 MDLVQSS--RKLIQDMIQLAGSQMKLL------LMDGETTPTVSCAFAQSEV----MQKEVYIFD 53

  Fly    76 EVAN------------VVYVMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEV 128
            .:.|            ||:| ||....:|:|...:    :.....||::.|....:...|.:|..
 Worm    54 RIENKTSSENIKNLKCVVFV-RPTPKNIERLVKEL----QEPRFSQYYLYFTNTINKYDVKRLAE 113

  Fly   129 SGVLGSFGNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKI 193
            :....:...::|:..:.:|:..||.::.:.:.| |.|......:..:...|::.|.....:.|.:
 Worm   114 ADKNETVREVQEVFLDGVPIRKDLFTLNLTHIF-DSSFTLKEEAAERIKCGIIALLLQLKKAPAV 177

  Fly   194 -YGKGE-FAHRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYG 256
             |.|.. ...:|.:...|..|.|..|:...:... .|::::||.|.::||..|.|||.:|.|...
 Worm   178 RYQKSSPSCKKVADDVAQFIRRENGLFENSRADT-TLLIIERSQDAVTPLLNQWTYEAMIHEMLT 241

  Fly   257 IRQNKLTLPAENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVT 321
            :..|:.|.                              |::..:|....::.:|.....:|.|:.
 Worm   242 LTNNRCTC------------------------------TDQNIVLSELHDEFFARNITANFGEIG 276

  Fly   322 KLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFAD 386
            :.:.....|...:.|.....:|:|::|.|||: .||........|:|.::.|.|...|.......
 Worm   277 QNIKTLISEFQEKKHINKNLESIQDMKKFVED-YPQFKKISGTVSKHVSLVGELSNLVQKHNLLG 340

  Fly   387 DLAAEQEFMVCADIDKPSAYIEDLI----ACRVELNRVLRLICMQCHAASGFK-EKLLNHYKREL 446
            ....||..:...|..|....:..|:    ...|::.|::.|..::...|.|.: ..|::..:.:.
 Worm   341 VSEVEQAIVSDGDHGKCINLVRGLLKNTKTREVDIIRLVLLYALRFENAPGNELNSLISQLRPQH 405

  Fly   447 VHVYGLEVLLTISNLEKSGLLHLQTESRAYSVLRKTLHLTVDDNVEIEPKDISYVHSFYAPLTAR 511
            ..::     .|:|.|.|.|.|     ||                   .|.|:     |....|..
 Worm   406 PKIH-----QTVSTLLKYGGL-----SR-------------------RPADL-----FGGESTID 436

  Fly   512 IVEHSLKPL-GWQTLKSQ----INNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRV---- 567
            |.:..:|.| |.:.:.:|    :.|:                    :.:...|.|.|.|.:
 Worm   437 ITKRFIKGLKGVENIYTQHSPYLKNM--------------------IESCQRGRLDNYPLLSNEC 481

  Fly   568 -----VLVCFVGGCTFAEIAALRFL---AAQEDNNVEFLIATTKVVNKHSFLD 612
                 ::|..|||.|:.|.|.:|.|   ..|.......::|.:.::|..|||:
 Worm   482 DRMDNIIVFIVGGATYEEAAYVRSLNEKRMQGYGGPAVVLAGSSMLNTKSFLE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	115/608 (19%)
vps-45	NP_741714.1	Sec1	23..528	CDD:279352	115/606 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910