Protein Alignment car and vps-33.1

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_498920.2
• Gene: vps-33.1 / 176221
• WormBaseID: WBGene00015130
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 161/641 - (25%)
• Similarity: 283/641 - (44%)
• Gaps: 124/641 - (19%)

  Fly    25 LLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLLAL-------KPELHLPREVANVVY 82
            |...||.::|:|.||.|...    .::.|..|||  |..:||.       ..|........:||:
 Worm    33 LFSVLDSLDGNKTIVWDRDR----SVMHRVNLFA--GASVLAAHGVVANHSIETKKSASTPHVVF 91

  Fly    83 VMRPRVALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSF----GNIEELAW 143
            .:.|.:..::.|..::. ..|..:...|.:.|.|....:....|:.... |.:    .:::|:..
 Worm    92 FLAPTMVSLDLLCDYID-NVRNDSKILYQVFFIPEAWFVVRESLKTRAE-GKYWERLESVKEIPL 154

  Fly   144 NYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQL-QRLYGRIP-------KIYGKGEFA 200
            .:||.|.:.:|:..|.....:.::||.:.|::.||.|.|| ....||..       .||.||::|
 Worm   155 CWLPRDGECLSLSSPQIAARLLINGDWTHLHKCAVALNQLIDMCRGRSSSSNQRPMSIYAKGKWA 219

  Fly   201 HRVWEHAKQLGR-------DERTLYNGD--KGV--VDQLILLDRSIDLLSPLATQLTYEGLIDEF 254
            ..|   ||.:|:       |..| .|.|  :|:  :::::|:||.:|.|:|:.:|||:.||:||.
 Worm   220 SDV---AKMMGKIRNSAEADSMT-KNLDPIEGLLKINRIVLIDRWMDPLTPMLSQLTFYGLLDEI 280

  Fly   255 YGIRQ-NKLTLPAENFPSDGALPGGGGSGPRVEESQSLLGD--TEKKTILLHSGEQLYAELRNKH 316
            |||.. |.:.:|...|.::..                  ||  .||:..|:   :::|..|::.|
 Worm   281 YGIGMVNSVKVPEMEFKNEKD------------------GDPFQEKEVYLI---DEVYHRLKHSH 324

  Fly   317 FN----EVTKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHE 377
            .|    |.:|:||    ||...........||.|....|:. :|:::.:||....|..:|.::..
 Worm   325 INAVSIEASKVLA----EIRDDEQFDRDKMSVAEYSVLVKK-MPKIINRKKMIEVHMRLAEMIQS 384

  Fly   378 QVNAVRFADDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHY 442
            .|.. :.:|.:..|::.:..:|.||....|||||.....||.|||||.:......|.|..:|.||
 Worm   385 HVYC-KQSDSIKLERDLLEYSDSDKAIPLIEDLIFDASPLNAVLRLISVHSLTCGGLKPSVLQHY 448

  Fly   443 KRELVHVYGLEVLLTISNLEKSGLLH-------LQTE--SRAYSVLRKTLHLTVDDNVEIEPKDI 498
            :|.:...||...|..:..::|.||:.       :|.|  ...:..::|...:..::..|.:..|:
 Worm   449 RRIVNQSYGSSALNKVLKMQKMGLIREKGGGGKMQCEYAQMMFQQMKKNHDMLPEEFSEAKLDDM 513

  Fly   499 SYVHSFYAPLTARIVEHS--LKPLGW-QTLKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGS 560
            :|.:|.::||..:::|..  :|.:|| :|:                     ||.:..:....:|
 Worm   514 AYAYSGFSPLLCKMLEEGDRVKWVGWPKTV---------------------IGDKSDLIAERDG- 556

  Fly   561 LLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDN--NVEFLIATTKVVNKHSFLDSL 614
                 |...|..:||.|.:|:|.:|      :|  ||. ||.|:.::.....|:::
 Worm   557 -----RGTCVFVIGGLTRSELAIIR------ENLPNVA-LITTSALITGDKLLNNI 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	156/620 (25%)
vps-33.1	NP_498920.2	Sec1	44..435	CDD:279352	113/429 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160155944
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53951
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	1	1.000	-	-		FOG0002117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101460
Panther	1	1.100	-	-	LDO	PTHR11679
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1650
SonicParanoid	1	1.000	-	-		X1571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.790