Protein Alignment car and AgaP_AGAP001463

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_321664.3
• Gene: AgaP_AGAP001463 / 1281712
• VectorBaseID: AGAP001463
• Length: 683
• Species: Anopheles gambiae
• Alignment Length: 687
• Identity: 150/687 - (21%)
• Similarity: 276/687 - (40%)
• Gaps: 103/687 - (14%)

  Fly    15 QLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLLALKPELHLPREVAN 79
            |:.||    :|......|...|.::::..:|.||:.|........:||..:......:.|.:...
Mosquito    14 QIAQE----KLQHVFYSIPSEKDLIIEPALIKPLEHVCGASWLRKKGIDKIFKFDSKNPPPKRKQ 74

  Fly    80 VVYVMRPRV----ALMEQLAAHVKAGGRA----AAGRQYHILFAPRRSCLCVSQLEVSGVLGSFG 136
            .||::...:    ::::|::.:.......    ...:|||:|..|.........||..|:.|
Mosquito    75 FVYLITSSLLTFKSVLDQISGYQSQTSSMMEPDIRNKQYHVLVLPSVLASFEHLLEEEGLHG--- 136

  Fly   137 NIEEL---AWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGE 198
             |.||   .|::|.||..|:|:|:||.|.||.|..||:.|...|..:.....:.|:...::..||
Mosquito   137 -IVELYNFQWDFLLLDESLLSLELPNVFADVFVRKDTTPLGSIAQSIRIFNLVMGKPHLVFSLGE 200

  Fly   199 FAHRVWEHAKQLGRDERTLYNGDK---GVVDQ---------LILLDRSIDLLSPLATQLTYEGLI 251
            .|.::....:::...:|....|.:   |.|||         :::|||..|..:.|.|.:.|.||:
Mosquito   201 NAEKILHMVQRMEAAKRPNVGGKENATGKVDQPEKEPEYSAMLILDRDRDYPACLLTPVVYCGLL 265

  Fly   252 DEFYGIRQNKLTLPAE-NFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQ--LYAELR 313
            .|...:....|.:..| |...:|.|......|......|      ::.|.|..||.|  :|.|.|
Mosquito   266 LEIQPLNSGSLAVDGECNKIKNGKLAFLQEQGAATASKQ------QETTSLRMSGAQDMIYLEHR 324

  Fly   314 NKHFNEVTKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQ 378
            .:||:||..||:.:|:.:.::..|.:::..:.|:|.:|.:.||::.|.||...:|..:...:.|:
Mosquito   325 YRHFSEVISLLSAQAKALGLEGKAYTREMKLHEMKEYVTHKLPKVAAAKKELFKHLRLCETIVEE 389

  Fly   379 VNAVRFADDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYK 443
            :.| .|......|:..:...:..:...||.:|::........|||||:. |...|...:.:....
Mosquito   390 IGA-NFEKHQMIEESILTNTNRKQIMNYILELLSSDAHRYNTLRLICLY-HVTIGLTGEDMTRLM 452

  Fly   444 RELVHVYGLEVLLTISNLEKSGLLHLQTESRAYSVLRKTLHLTVDDNVEIE-------PKDI--- 498
            ...::.:|...|....:|.::.|....|......:|.:....|:....:||       |.|.
Mosquito   453 TGYLNAFGYRHLSLFHSLFQARLFPDTTNLSKTKILSQISIPTLKTPFQIEANKLKQLPTDANDT 517

  Fly   499 ----------------------------------SYV-HSFYAPLTARIVEHSLKPLGWQTLKSQ 528
                                              ||| :..|.||..::.........:..|.::
Mosquito   518 ATTATTPTTDRDGGLTGGVQSTGGSVAAGGKTCPSYVFNGNYIPLVTQLTNLIFAASSFDNLNTR 582

  Fly   529 INNLPGPTFEDFQAQLVGIGGRHT---------VTTVSEGSLLN--VP---RVVLVCFVGGCTFA 579
            :.:|.............|..|.||         ::..|....||  :|   :.:.:..|||.|:|
Mosquito   583 LGHLERLKVSGRLLTASGQPGDHTQCAPRSIKELSASSHKVALNQLLPFKEKTMFIFIVGGITYA 647

  Fly   580 EIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMS 616
            ||||...|  :.....:.::::.:::..|..::|:::
Mosquito   648 EIAACHLL--ERTIGAKIVLSSDRIIAGHDLIESVVN 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	143/654 (22%)
AgaP_AGAP001463	XP_321664.3	Sec1	31..441	CDD:279352	105/421 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53951
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830