Protein Alignment car and AgaP_AGAP003203

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_312907.4
• Gene: AgaP_AGAP003203 / 1273876
• VectorBaseID: AGAP003203
• Length: 605
• Species: Anopheles gambiae
• Alignment Length: 620
• Identity: 305/620 - (49%)
• Similarity: 425/620 - (68%)
• Gaps: 22/620 - (3%)

  Fly     1 MFPHLKGHGQRVNLQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGI-RL 64
            |:.||.  |.|.|:|||||||.||.::.|||.||:|.|:.||::.||:.||.|.....:..: ::
Mosquito     5 MYSHLS--GGRANVQLLQEAAVREFVKILDRCEGTKAIIWDESLGGPVGLVARYTFLKEHHVTKM 67

  Fly    65 LALKPELHLPREVANVVYVMRPRVALMEQLA--AHVKAGGRAAAGRQYHILFAPRRSCLCVSQLE 127
            ..|:.|.....:|.|::::.||...||:.:|  .|.:...|..:.::|.:.|.|::|.||..:|:
Mosquito    68 YPLRSEAWTDIDVKNIIFITRPHQTLMDYIANNIHEEERKRKVSRKEYFLYFLPKKSFLCEKRLQ 132

  Fly   128 VSGVLGSFGNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPK 192
            :.||.||...|.|....:.|.|.||:|||:.:|::::.::||||||:|:|..||.||:|||||||
Mosquito   133 IKGVHGSLSYIGEFRCEFFPFDNDLLSMELKDAYKEIYLEGDTSSLHQSACALVALQKLYGRIPK 197

  Fly   193 IYGKGEFAHRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGI 257
            :||.|.:|.||||..|.|..::..:.|.:|||:||:|:||||.||:|.|||||||||||||.:||
Mosquito   198 VYGIGGYAQRVWEMTKALTEEDGHVMNSEKGVIDQMIILDRSTDLMSVLATQLTYEGLIDEIFGI 262

  Fly   258 RQNKLTLPAENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTK 322
            ....:.||||.|.:     |.|.|..|         :|||...:|:|.||||||||:|:||.|..
Mosquito   263 NNTTVNLPAEKFNT-----GEGLSTDR---------NTEKSQFILNSKEQLYAELRDKNFNAVGA 313

  Fly   323 LLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADD 387
            :|:|.|:.|..:.:....:||:||:|.|||: ||.:.:.:::.:.||.||.|:.:.:::..|.|.
Mosquito   314 VLSRMAKSIRSRANENHGEKSIQELKKFVES-LPHIKSNEQSLATHTTIAELVQDVISSHAFLDV 377

  Fly   388 LAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGL 452
            |..||||::|:|:|||:::|||:||....|..||||||||..|.:|.|.|:|::||||||.||||
Mosquito   378 LGCEQEFLLCSDVDKPNSFIEDMIAKEAPLRSVLRLICMQSIAGTGLKPKVLDYYKRELVQVYGL 442

  Fly   453 EVLLTISNLEKSGLLHLQTESRAYSVLRKTLHLTVDDNVEIEPKDISYVHSFYAPLTARIVEHSL 517
            :.|||:.||||:|||..||.||.|.||||||:||.:...|:.||||:||||.||||:.||:|..|
Mosquito   443 KTLLTLGNLEKAGLLRQQTGSRTYHVLRKTLNLTAETPEEVSPKDITYVHSIYAPLSVRIIEQHL 507

  Fly   518 KPLGWQTLKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIA 582
            ||.|||.|..::::|||||||||||.......|.:.|  ||.|..::|||::|.||||||||||:
Mosquito   508 KPNGWQLLTEKLSSLPGPTFEDFQASPSLSSRRGSFT--SELSQSDIPRVIVVFFVGGCTFAEIS 570

  Fly   583 ALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMSS 617
            ||||||.|:||||||||.|||::||::||||.:.:
Mosquito   571 ALRFLAQQDDNNVEFLICTTKLINKNTFLDSFIEN 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	279/572 (49%)
AgaP_AGAP003203	XP_312907.4	Sec1	38..594	CDD:279352	279/572 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	539	1.000	Domainoid score	I964
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11294
Inparanoid	1	1.050	574	1.000	Inparanoid score	I2558
OMA	1	1.010	-	-		QHG53951
OrthoDB	1	1.010	-	-		D406738at2759
OrthoFinder	1	1.000	-	-		FOG0002117
OrthoInspector	1	1.000	-	-		oto107045
Panther	1	1.100	-	-	LDO	PTHR11679
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1571
TreeFam	1	0.960	-	-
	13	12.940