Protein Alignment car and AgaP_AGAP003023

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_311854.4
• Gene: AgaP_AGAP003023 / 1272929
• VectorBaseID: AGAP003023
• Length: 587
• Species: Anopheles gambiae
• Alignment Length: 672
• Identity: 134/672 - (19%)
• Similarity: 252/672 - (37%)
• Gaps: 165/672 - (24%)

  Fly    16 LLQEAACRELLQQLDRIEGS-----KVIVLDETMIGPLDLVTRPKLFADRGIRLLALKPELHLPR 75
            |:.:....|:::...:.:|.     :::::|:..:..:...|:....:..|:.|:....:...|.
Mosquito     6 LVGQKIMNEVVRSKTKSDGKPGTEWRILIVDKLAMRMVSACTKMHEISAEGVTLVEDINKKREPL 70

  Fly    76 EVANVVYVMRPRV----ALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQL--EV--SGVL 132
            .....||::.|..    .||.......|...:||     |:.|..    :|..:|  ::  |.|.
Mosquito    71 PAIEAVYLITPSEDSIRLLMRDFENPAKPTYKAA-----HVFFTE----VCPEELFNDICKSVVS 126

  Fly   133 GSFGNIEELAWNYLPLDVDLVSMEMPNAFR----DVSVDGDTSSLYQAAVGLVQLQRLYGRIPKI 193
            .....::|:...:||.:..:.|::.|..|:    .......:.::.:.|..:..|....|..|.:
Mosquito   127 RKIKTLKEINIAFLPYESQVYSLDSPVTFQCAYSPALASARSGNMERIAEQIATLCATLGEYPSV 191

  Fly   194 Y------GKGEFAHRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLID 252
            .      |..|.|..|.:.......||.|:..|.:....||::|||..|.:|||..:||.:.:..
Mosquito   192 RYRSEWDGNVELAQMVQQKLDAYKADEPTMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAY 256

  Fly   253 EFYGIRQNKLTLPAEN-----FPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAEL 312
            :.         ||..|     .||..|                     .:|.:||...:.|:.:|
Mosquito   257 DL---------LPIVNDVYKFIPSPNA---------------------AEKEVLLDENDDLWVDL 291

  Fly   313 RNKHFNEVTKLLARKAREIHVQMHATSQDK-SVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLH 376
            |::|...|::.:.:..:........|..:| |::::...::. :||...|....|.|      ||
Mosquito   292 RHQHIAVVSQSVTQYLKSFTESKRLTQSEKQSMKDLSQMIKK-MPQYQKQLSKYSTH------LH 349

  Fly   377 EQVNAVRFADDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNH 441
                   .|:|.....:           .|::.|  ||||.:     :.|...|..   ||:.:|
Mosquito   350 -------LAEDCMKSYQ-----------GYVDKL--CRVEQD-----LAMGTDAEG---EKIKDH 386

  Fly   442 YKR-------------ELVHVYGLEVL----LTISNLEKSGLLHLQTESRAYSVLRKTLHLTVDD 489
            .:.             :.|.:..|.|:    ::..||.|. :.|.|.:.:...::...:||.::.
Mosquito   387 MRNIVPILLDQNVSNYDKVRIIALYVMIKNGISEENLTKL-VTHAQIDQKEREMIHNLIHLGINV 450

  Fly   490 NVEIEPKDISYVHSFYAPLTARIVEHSLKPLGWQTLKSQINNLPGPTFEDFQAQLVG-------- 546
            ..:...|     .|:..|...||.||:.:...|.           |..:|.....:.
Mosquito   451 IADGNRK-----KSYTVPRKERINEHTYQMSRWT-----------PVIKDIMEDAIDNKLDERHF 499

  Fly   547 --IGGR-----HTVTTV---------SEGSLLNVPRVVLVCFVGGCTFAEI-AALRFLAAQEDNN 594
              :|||     |..|:.         |:.::.||||:::. .||||:::|| .|....||.:  |
Mosquito   500 PFLGGRKMAGFHAPTSARYGHWHKDKSQTAVKNVPRLIMF-VVGGCSYSEIRCAYEVTAAVK--N 561

  Fly   595 VEFLIATTKVVNKHSFLDSLMS 616
            .|..|.::.::...:||..|.|
Mosquito   562 WEVYIGSSHILTPETFLSDLGS 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	127/635 (20%)
AgaP_AGAP003023	XP_311854.4	Sec1	31..574	CDD:279352	127/636 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810