Protein Alignment car and AgaP_AGAP011358

DIOPT Version :9

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_309291.4
• Gene: AgaP_AGAP011358 / 1270593
• VectorBaseID: AGAP011358
• Length: 660
• Species: Anopheles gambiae
• Alignment Length: 711
• Identity: 149/711 - (20%)
• Similarity: 254/711 - (35%)
• Gaps: 163/711 - (22%)

  Fly     2 FPHLKGHGQRVNL-QLLQEAACRELLQQL---DRIEGSKVIVLDETMIGPLDLVTRPKLFADRGI 62
            |..|....|.:|| |.:.:|...|.:.:|   ||:        .:.:|.||..:   :...:.||
Mosquito     5 FSFLDAIKQMLNLNQPITKAISAEPVWKLLIYDRV--------GQDIISPLISI---RELREMGI 58

  Fly    63 RLLALKPELHLPREVANVVYVMRPRVALMEQLAAHVKAGGRAAAGRQ------YHILF-AP---- 116
               .|..:||..|:....|..:...||..|.|       ||.|...|      ||:.| ||
Mosquito    59 ---TLHIQLHSDRDSIPDVPAIYFCVATEENL-------GRIAQDFQNGLYDVYHLNFIAPISRQ 113

  Fly   117 RRSCLCVSQLEVSGVLGSFGNIEELAWNYLPLDVDLVSMEMPNA------------FRDVS---- 165
            |...|..:.|: :|.:.:...:.:...|::.|:.|:..::..|:            ..||.
Mosquito   114 RLEDLAAAALQ-AGCVANIHKVYDQYLNFITLEDDMFVLKHQNSDALSYYAINRANTEDVEMENI 177

  Fly   166 VDGDTSSLYQAAVGLVQLQRLYGRIPKI----YGKGEFAHR---------VWEHAKQLGRDERTL 217
            :|....||:...|.|       |.:|.|    ....|...|         :|:....|...:.|.
Mosquito   178 MDSIVDSLFAVFVTL-------GTVPIIRCPKNSAAEMVARKLEKKLRENLWDARNNLFHMDATQ 235

  Fly   218 YNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLPAENFPSDGALPGGGGSG 282
            ..........|:||||:||:.:||....||:.|..:...:..|::.:..:.........|..|:.
Mosquito   236 TGAFSFQRPLLVLLDRTIDMATPLHHTWTYQALAHDVLELALNRVMVEEDPSADQQQQYGATGAK 300

  Fly   283 PRVEESQSLLGDTEKKTILLHSG-------EQLYAELRNKHFN--EVTKLLARKAREIHVQMHAT 338
            |:::....   |...:....|.|       |.:..||.....:  |:.||......:.......:
Mosquito   301 PKMKACDL---DARDRFWCTHKGSPFPTVAEAIQEELEQYRSSEEEIKKLKTTMGIDGESDAAFS 362

  Fly   339 SQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAAEQEFMVCADIDKP 403
            ..:.:..::.|.| |.||||:.:|:....||.||..:...:.:.|.......|::.|....:|:.
Mosquito   363 MVNDNTAKLTSAV-NSLPQLLEKKRLIDMHTKIATSILNYIKSRRLDSFFELEEKIMSKQALDRA 426

  Fly   404 -SAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLLTISNLEKSGLL 467
             |..::|......|....|.:|...|...|.      ..:||       :|..|.....:.|.|.
Mosquito   427 LSEVLKDPEFGLPEDKMRLFIIYYICSNVSD------GEFKR-------IEETLRECGCDLSPLP 478

  Fly   468 HLQTESRAYSVLRKTLHLTVDDN---------VEIEPKDISYVHSFYAP-LTARIVEHSLKPLGW 522
            ::|   |..|:::.||   .:.|         |.:..|.:|...||... :...:|:..::.|..
Mosquito   479 YIQ---RWKSIMKSTL---TNSNQYEGSGTKTVSMFSKLVSQGSSFVMEGVKNLVVKRHVRILAK 537

  Fly   523 QTL-KSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSE---------GS-----------LLNVPR 566
            ..| |.:::|.|         ..:.:    .||.::|         ||           ||....
Mosquito   538 SCLFKGKLDNYP---------LFINL----PVTKITEQLMECRSGGGSEVDDYLYLDPKLLKGSD 589

  Fly   567 VV----------LVCFVGGCTFAEIAAL-RFLAAQEDNNV--EFLIATTKVVNKHSFLDSL 614
            ||          :|..|||..:.|...| .|:.:::..|.  ..:...:.:.|...||..|
Mosquito   590 VVPKNRAPFQDAIVFVVGGGNYIEYQNLVDFIKSKQSTNSIRRIIYGASTLTNAKQFLKQL 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..606	CDD:279352	134/663 (20%)
AgaP_AGAP011358	XP_309291.4	Sec1	32..451	CDD:279352	95/451 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810