Protein Alignment Grip84 and SPC98

DIOPT Version :10

• Sequence 1: NP_728264.1
• Gene: Grip84 / 32946
• FlyBaseID: FBgn0026430
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_014273.1
• Gene: SPC98 / 855597
• SGDID: S000005070
• Length: 846
• Species: Saccharomyces cerevisiae
• Alignment Length: 746
• Identity: 137/746 - (18%)
• Similarity: 254/746 - (34%)
• Gaps: 248/746 - (33%)

  Fly   212 SGYRSVTNKTGNSPKSMPNDLVTLTDVPDE----YRTHLL---------WEYYKVD-GDKVPRAE 262
            |.|.|||.:..::|       ..:..:|:|    |.::.|         :::.::. ..|:|..|
Yeast   160 STYSSVTLRQLSNP-------YYVNTIPEEDILKYVSYTLLATTSALFPFDHEQIQIPSKIPNFE 217

  Fly   263 IAAMPLLSQESMLLDELLHCLTGIRESLLVPQKPIISAVGLAKYDTDFDIHTHLDRSLTHQVREI 327
            ...:.|:.:..:|...|.:.:...|...:.|.|..:    :.:...:...:|....:|... ..:
Yeast   218 SGLLHLIFEAGLLYQSLGYKVEKFRMLNISPMKKAL----IIEISEELQNYTAFVNNLVSS-GTV 277

  Fly   328 LPLASYFMGVQKIIAATDGLGQVMNSLNEALQELTHDFYLIIVQAEQELR----HNRLTLQKLLY 388
            :.|.|.:..:.:.|...    ::.....|.|:||:.|.:||      ||.    |..||::|
Yeast   278 VSLKSLYREIYENIIRL----RIYCRFTEHLEELSGDTFLI------ELNIFKSHGDLTIRK--- 329

  Fly   389 YLQPTMWVMHEVWSSLVIIQLSDSRDAEVLTYLHERIKRLEGNKDAQQLIIGLVRKAAKPYMRML 453
                   :...:::|::.:                                         |...|
Yeast   330 -------IATNLFNSMISL-----------------------------------------YYEYL 346

  Fly   454 QMWIQKGVIVDRHREFLVVDNEVIHRDELPEHYSDDY-WERRYTLRDEQIPSFLAK-YSDKILRT 516
            ..|:.||::...:.||.:.:|...:..:      ||: :........|::|:|:.| .:.||...
Yeast   347 MNWLTKGLLRATYGEFFIAENTDTNGTD------DDFIYHIPIEFNQERVPAFIPKELAYKIFMI 405

  Fly   517 GK-YLNVIRQCGKRVMPTQEMNLE----FDPTSERHVS-----VINDAYYFAARMLLDVLLTEND 571
            || |:.:.:.| |.|..|.|.:.:    :...|.|.:|     :|||.|       .:::...|.
Yeast   406 GKSYIFLEKYC-KEVQWTNEFSKKYHVLYQSNSYRGISTNFFEIINDQY-------SEIVNHTNQ 462

  Fly   572 LMG---HLQSV----KRYLLLNQGDFTMQFMDACEDELTKNVDHVLPMTLENLLGLTLRISSAR- 628
            ::.   |.:.|    |..||:.:.||....::...|.|....|.:....|..:|...:::||.|
Yeast   463 ILNQKFHYRDVVFALKNILLMGKSDFMDALIEKANDILATPSDSLPNYKLTRVLQEAVQLSSLRH 527

  Fly   629 --NDPYKDDLHCELLPYDLVTQMSKIMKKEENWQAQPRLDLS----GLECFAFTYEVKWPCSLVL 687
              |.|                :.|.::    |......|||.    |.:.|...|.:..|.||||
Yeast   528 LMNSP----------------RNSSVI----NGLDARVLDLGHGSVGWDVFTLDYILYPPLSLVL 572

  Fly   688 N---------HISISKYQMLFRQ--LFYCKHVERQLCKIWKENSIARQFEPQAA----------S 731
            |         ::.|..:...|::  .||.|       ::.|.|.|.|.|:....          .
Yeast   573 NVNRPFGRKEYLRIFNFLWRFKKNNYFYQK-------EMLKSNDIIRSFKKIRGYNPLIRDIINK 630

  Fly   732 LYRAAFTLRQRMMNAIQNLEYYMMIEIIEPNWHIFIEKMKTVE---------------------- 774
            |.|.:. ||.:.......:|.|.:..|||.|:.....|::..|
Yeast   631 LSRISI-LRTQFQQFNSKMESYYLNCIIEENFKEMTRKLQRTENKSQNQFDLIRLNNGTIELNGI 694

  Fly   775 -------------------------NVDNVLRLHQDFLDSCLKNCML-TESSHLN---------- 803
                                     |:|.:..:|..||.:.|.:.:. |.:|.::
Yeast   695 LTPKAEVLTKSSSSKPQKHAIEKTLNIDELESVHNTFLTNILSHKLFATNTSEISVGDYSGQPYP 759

  Fly   804 -------RSIFKLCKICLKYCEFIQITQRYF 827
                   .|:::..|:   ||....|....|
Yeast   760 TSLVLLLNSVYEFVKV---YCNLNDIGYEIF 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	GCP_N_terminal	276..569	CDD:465456	54/308 (18%)
		GCP_C_terminal	572..912	CDD:461187	67/356 (19%)
SPC98	NP_014273.1	GCP_N_terminal	185..467	CDD:465456	62/361 (17%)
		GCP_C_terminal	476..823	CDD:461187	65/343 (19%)