DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Grip84 and SPC98

DIOPT Version :9

Sequence 1:	NP_728264.1	Gene:	Grip84 / 32946	FlyBaseID:	FBgn0026430	Length:	926	Species:	Drosophila melanogaster
Sequence 2:	NP_196286.1	Gene:	SPC98 / 830557	AraportID:	AT5G06680	Length:	838	Species:	Arabidopsis thaliana

Alignment Length:	815	Identity:	179/815 - (21%)
Similarity:	318/815 - (39%)	Gaps:	193/815 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 VLNAVSDQSLSGYRSVTNK----------TGN--------SPKSMPNDLVTLTDVPDEYRTHLLW 248
            :|..|||...|....:.:.          |||        ..|...|.::.::..|:..|.....
plant   108 LLKIVSDDRKSAINGLDSSVLLPNLGIGDTGNGVLSRGEAKKKDWSNGVLLVSKDPENLRDIAFR 172

  Fly   249 EYYKVDGDKVPRAEIAAMPLLSQESMLLDELLHCLTGIRESLLVPQKPIISAVGL----AKYDTD 309
            ||               ..|:.:|:.:.:|:|     :|:.|...|       |:    .|::::
plant   173 EY---------------AILVKEENEVTEEVL-----VRDVLYASQ-------GIDGKYVKFNSE 210

  Fly   310 FDIH-----THLDRSLTHQVREILPLASYFMGVQKIIAAT------DGLGQVMNSLNEALQELTH 363
            .|.:     ..:.|:....||.:..|...|..|:..|..:      :.:|.|..:...|||:...
plant   211 IDGYAVQESVKVPRATRIMVRMLSELGWLFRKVKTFITESMDRFPAEDVGTVGQAFCAALQDELS 275

  Fly   364 DFY--LIIVQA----------EQELRHNRLTLQKLLYYLQPTMWVMHEVWSSLVIIQLSDSRDAE 416
            |:|  |.:::|          |....:|.|:|::|            .||.:..::::      .
plant   276 DYYKLLAVLEAQAMNPIPLVSESASSNNYLSLRRL------------SVWFAEPMVKM------R 322

  Fly   417 VLTYLHERIKRLEGNKDA--------------QQLIIGLVRKAAKPYMRMLQMWIQKGVIVDRHR 467
            ::..|.::.|.|.|...|              ...::.|:|....|...|::.|:.:|.:.|...
plant   323 LMAVLVDKCKVLRGGAMAGAIHLHAQHGDPLVHDFMMSLLRCVCSPLFEMVRSWVLEGELEDTFG 387

  Fly   468 EFLVVDNEVIHRDELPEHYSDDYWERRYTLRDEQIPSFLA-KYSDKILRTGKYLNVIRQC----- 526
            ||.||...|         ..|..|...|.|....:|||:: ..:.:||||||.:|.:|.|
plant   388 EFFVVGQPV---------KVDLLWREGYKLHPAMLPSFISPSLAQRILRTGKSINFLRVCCDDHG 443

  Fly   527 ---------GKRVMPTQEMNLEFDPTSE-RHVSVINDAYYFAARMLLDVLLTENDLMGHLQSVKR 581
                     ......|:...|.:..|.. .|  ::.:|.....:.|||||........|..::||
plant   444 WADAASEAAAASGTTTRRGGLGYGETDALEH--LVTEAAKRIDKHLLDVLYKRYKFKEHCLAIKR 506

  Fly   582 YLLLNQGDFTMQFMDACEDELTKNVDHVLPMTLENLLGLTLRISSARND--PYKDDLHCELLPYD 644
            ||||.||||....||....:|::..:::....|...|...:|.|:|:.|  ...|.|..:::|:.
plant   507 YLLLGQGDFVQYLMDIVGPKLSEPANNISSFELAGFLEAAIRASNAQYDDRDMLDRLRVKMMPHG 571

  Fly   645 LVTQMSKIMKKEENWQAQPRLDLSGLECFAFTYEVKWPCSLVLNHISISKYQMLFRQLFYCKHVE 709
                     ..:..|           :.|:..||.:.|...|.....:|||..:|..|:..|.||
plant   572 ---------SGDRGW-----------DVFSLEYEARVPLDTVFTESVLSKYLRVFNFLWKLKRVE 616

  Fly   710 RQLCKIWK--------ENSIAR---QFEPQAASLYRAAFTLRQRMMNAIQNLEYYMMIEIIEPNW 763
            ..|..|||        .||..:   ..:.|..|..|....|...|.:.:.|.:||:|.|::|.:|
plant   617 HALIGIWKTMKPNCITSNSFVKLQSSVKLQLLSALRRCQVLWNEMNHFVTNFQYYIMFEVLEVSW 681

  Fly   764 HIFIEKMKTVENVDNVLRLHQDFLDSCLKNCMLTESSH-LNRSIFKLCKICLKYCEFIQITQRYF 827
            ..|.::|:..:::|::|..|:.:|::.:...:|.|.|. :..|:|.|.::.|::...........
plant   682 SNFSKEMEAAKDLDDLLAAHEKYLNAIVGKSLLGEQSQTIRESLFVLFELILRFRSHADRLYEGI 746

  Fly   828 QDAELRSMVRDSADSSESEQESLHCPQIETPLDPTDTFSERVRRFDLEFTQLLISFLKQINSMAK 892
            .:.::||  ::|.......||            |....||..:.......:.|.|..:.::|:||
plant   747 HELQIRS--KESGREKNKSQE------------PGSWISEGRKGLTQRAGEFLQSMSQDMDSIAK 797

  Fly   893 KNTA--DCFMNLV------------HRINFNAFYT 913
            :.|:  |.|::|:            .|::|..||:
plant   798 EYTSSLDGFLSLLPLQQSVDLKFLFFRLDFTEFYS 832

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	Spc97_Spc98	278..795	CDD:282045	135/586 (23%)
SPC98	NP_196286.1	GCP_N_terminal	190..493	CDD:407574	72/338 (21%)
SPC98	NP_196286.1	Spc97_Spc98	499..831	CDD:398000	87/365 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910