DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Grip84 and GCP4

DIOPT Version :9

Sequence 1:	NP_728264.1	Gene:	Grip84 / 32946	FlyBaseID:	FBgn0026430	Length:	926	Species:	Drosophila melanogaster
Sequence 2:	NP_190944.2	Gene:	GCP4 / 824543	AraportID:	AT3G53760	Length:	745	Species:	Arabidopsis thaliana

Alignment Length:	806	Identity:	146/806 - (18%)
Similarity:	287/806 - (35%)	Gaps:	248/806 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 LLDELLHCLTGIRESLLVPQKPIISAVGLAKYDTDFDIH-----------THLDRSLTHQVREIL 328
            :|.|||..|.|....|:|.::.....:||| :::|..:.           :.::.|....:..::
plant     1 MLHELLLALLGFTGDLIVDEREQRKTLGLA-FNSDSPLSDECTFKLAPDISFIEPSERDLIERLI 64

  Fly   329 PLASYFMGVQKII--------------------------------------AATDGLGQVMNSLN 355
            .|..|:..:.:..                                      |..:|:|::::...
plant    65 KLGFYYRELDRFAKKSRNLSWIRSVTSVHPLERADELSKQSREKKPSVYRRAIANGIGEILSVYR 129

  Fly   356 EALQELTHDFYLIIVQAEQELRHNRLTLQKLLYYLQPTMWVMHE-----------VWSSLVIIQL 409
            .|:..:.                     ||||....|.:..:.|           ::..::.|:.
plant   130 SAVLHIE---------------------QKLLAETTPILATVTEGLNKFFVLFPPLYEVILEIER 173

  Fly   410 SDSRDAEVLTYLHERIKRLEGNKDAQQLIIGLVRKAAKPYMRMLQMWIQKGVIVDRHREFLVV-- 472
            .|.|..::|..|::|...  |..:.:..:..|:....:.....|..|:..|::.|.|.||.:.
plant   174 DDIRGGQLLNVLNKRCHC--GVPELRTCLQRLLWNGHQVMYNQLAAWMVYGILQDPHGEFFIKRQ 236

  Fly   473 -DNEVIHR---DELPE--------HYSDDYWERRYTLRDEQIPSFL-AKYSDKILRTGKYLNVIR 524
             |.::.||   :|:.|        ..|...|...:.:..:.:|.:: .:..:.||..||.:.|:|
plant   237 DDGDLDHRSSQEEVSEKLARTSVHETSLTDWHSGFHISLDMLPDYIPMRLGESILFAGKAIRVLR 301

  Fly   525 ------------------QCGKRV-------MPTQEMNLEFDPT--------------------- 543
                              :..:|:       .|..|..|:.|.|
plant   302 NPSPAFQFQKDKSFQQTMRGSQRIRGFMHSDFPETETELDADLTGGELLPQSEADKIEAMLKDLK 366

  Fly   544 --SERH----VSVINDAYYFAARMLLDVLLTENDLMGHLQSVKRYLLLNQGDFTMQFMDACED-- 600
              ||.|    ...::.....||..|..:::...||.|||:::|.|.||.:|||...|::....
plant   367 ESSEFHKRSFECTVDSVRAIAASHLWQLVVVRADLNGHLKALKDYFLLEKGDFFQCFLEESRQLM 431

  Fly   601 -----ELTKNVDHVLPMTLENL-------------------LGLTLRISSARNDPYKDDLHCELL 641
                 :.|...|.::|..|...                   .|:|:|.|.|
plant   432 RLPPRQSTGESDLMVPFQLAATKTIAEEDKYFSRVSLRMPSFGVTVRSSQA-------------- 482

  Fly   642 PYDLVTQMSKI-MKKEENWQAQPRLDLSGLECFAFTYEVKWPCSLVLNHISISKYQMLFRQLFYC 705
              |:|  .||: :..:.|..:...:|  |.:..|..|.|.||..|......:|||..:|:.|...
plant   483 --DMV--RSKVSLTGKANLTSDTSVD--GWDAIALEYSVDWPMQLFFTQEVLSKYLKVFQYLIRL 541

  Fly   706 KHVERQLCKIW--------------KENSIARQFEPQAASLYRAAFTLRQRMMNAIQNLEYYMMI 756
            |..:.:|.|.|              :::.:......|.....|..:.:|:.|...|:||::|:.:
plant   542 KRTQMELEKSWASVMHQDHIESAQHRKDGLNGSTSQQRRQGIRPMWRVREHMAFLIRNLQFYIQV 606

  Fly   757 EIIEPNWHIFIEKMKTVENVDNVLRLHQDFLDSCLKNCMLTESSHLNRSIFKLCKICLKYCEFIQ 821
            ::||..|.:....:...::...::..||::|.:.:....|...| ::|.:..:.|:||::|..|:
plant   607 DVIESQWKVLQTHIHDSQDFTELVGFHQEYLSALISQSFLDIGS-VSRILDSIMKLCLQFCWNIE 670

  Fly   822 ITQRYFQDAELRSMVRDSADSSESEQESLHCPQIETPLDPTDTFSERVRRFDLEFTQLLISFLKQ 886
                           ...::.:.||.|::           .:.|:::        :..|.:.|:.
plant   671 ---------------NQESNPNTSELENI-----------AEEFNKK--------SNSLYTILRS 701

  Fly   887 INSMAKKNTADCFMNLVHRINFNAFY 912
             :.:|....|......:.|:|||:||
plant   702 -SKLAGSQRAPFLRRFLLRLNFNSFY 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	Spc97_Spc98	278..795	CDD:282045	123/684 (18%)
GCP4	NP_190944.2	GCP_N_terminal	50..302	CDD:407574	41/274 (15%)
GCP4	NP_190944.2	Spc97_Spc98	403..726	CDD:398000	76/378 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910