Protein Alignment Grip84 and Grip91

DIOPT Version :10

• Sequence 1: NP_728264.1
• Gene: Grip84 / 32946
• FlyBaseID: FBgn0026430
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Alignment Length: 980
• Identity: 204/980 - (20%)
• Similarity: 371/980 - (37%)
• Gaps: 275/980 - (28%)

  Fly     4 PHALRGVLANLISESQSPLTPESIIREFRATSDRRLPACDLIKVLVSISEKRPNFAEVTKEISHI 68
            ||....::.:|::     :|..|...:..|:.|.|....:|.::|||    |.|
  Fly   105 PHMRHSLMTHLLT-----MTDNSDAEKAVASEDPRTQCDNLTQILVS----RLN----------- 149

  Fly    69 LQNKDPMYALLVFVERYSECKPVSESSSSTSLSAMGLPHGNKTSDVNSAAGSVPTTLAIASTSTI 133
                                   |.|||..||:.||:.:||       ..|:...|.|.|.|...
  Fly   150 -----------------------SISSSIASLNEMGVVNGN-------GVGAAAVTGAAAVTGAA 184

  Fly   134 LTTSQNVSGSTRLSLTQSQDFPTSTPVNCKKATESDTTPVVFVRRGPMDRNRGAGK---DERNDL 195
            ..|  ..:..|..:.:.|.|           ||:|.    :.:|:..:.....|.|   :.|:|:
  Fly   185 AVT--GAAAVTGAAASHSYD-----------ATQSS----IGLRKQSLPNYLDATKMLPESRHDI 232

  Fly   196 SVIKERVLNAVSDQSLSGYRSVTNKTGNSPKSMPNDLVTLTDVPDEYRTHLLWEYYKVDGDKVPR 260
                  |::|           :.:.||...|.:..|:||              ..:|:|...:
  Fly   233 ------VMSA-----------IYSFTGVQGKYLKKDVVT--------------GRFKLDQQNI-- 264

  Fly   261 AEIAAMPLLSQESMLLDELLHCLTGIRESLLVPQKPIISAVGLAKYDTDFDIHTHLDRSLTHQVR 325
                ......|..|||.                    :|.:|          :.| ||.:.
  Fly   265 ----KFLTTGQAGMLLR--------------------LSELG----------YYH-DRVVK---- 290

  Fly   326 EILPLASYFMGVQKIIAATDGLGQVMNSLNEALQELTHDFYLIIVQAEQELRHNR---------- 380
                    |..|.....|...:||.:.|   .|:|...:|:..:.....|::..|
  Fly   291 --------FSDVSTGFNAIGSMGQALIS---KLKEELANFHGQVAMLHDEMQRFRQASVNGIANK 344

  Fly   381 ------------LTLQKLL-YYLQPTMWVMHEV-WSSLVIIQLSDSRDAEVLTYLHERIKRLEGN 431
                        :||.||| :|::|    :|.: |.:.:.......:..::.:.:::.:.  .||
  Fly   345 GKKDSGPDAGDEMTLFKLLAWYIKP----LHRMQWLTKIADACQVKKGGDLASTVYDFLD--NGN 403

  Fly   432 KDAQQLIIGLVRKAAKPYMRMLQMWIQKGVIVDRHREFLVVDNEVIHRDELPEHYSDDYWERRYT 496
            ....:|:..|:.....|.:||:..||.:|.|.|.||||.|...:.:..|.|        |..::.
  Fly   404 DMVNKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFVKSIKDVGVDRL--------WHDKFR 460

  Fly   497 LRDEQIPSFL-AKYSDKILRTGKYLNVIRQ-CGKRVMPTQEMNL------------EFDPTSERH 547
            ||...:|.|: ...::|||.|||.:|.:|: |.::.|..:...|            .:.|.:..|
  Fly   461 LRLPMLPKFVPMDMANKILMTGKSINFLREICEEQGMMKERDELMKVMESSASQIFSYTPDTSWH 525

  Fly   548 VSVINDAYYFAARMLLDVLLTENDLMGHLQSVKRYLLLNQGDFTMQFMDACEDELTKNVDHVLPM 612
            .:| ...|...::.:||:::..:.|:.||..::|||||.||||....::..::||.:....:...
  Fly   526 AAV-ETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELERPGLDIYAN 589

  Fly   613 TLENLLGLTLRISSAR-NDPYKDDLHCELLPYDLVTQMSKIMKKEENWQAQPRLDLSGLECFAFT 676
            .|.::|...||.::|: :||            |::..:..|:::..|...       |....:..
  Fly   590 DLTSMLDSALRCTNAQYDDP------------DILNHLDVIVQRPFNGDI-------GWNIISLQ 635

  Fly   677 YEVKWPCSLVLNHISISKYQMLFRQLFYCKHVERQL-CKIWKEN-SIARQFEPQAASLYRAAFTL 739
            |.|..|.:.:|.. ::..|::||:.|:..||:|..| .|||||. ..|:......:.:.:|:..|
  Fly   636 YIVHGPLAAMLES-TMPTYKVLFKPLWRMKHMEFVLSMKIWKEQMGNAKALRTMKSEIGKASHRL 699

  Fly   740 R---QRMMNAIQNLEYYMMIEIIEPNWHIFIEKMKTVENVDNVLRLHQDFLDSCLKNCMLTESSH 801
            .   ..:|:.|..::||::.|:||.||....:||:....:|.:|..|:.||.:.|..|.::..:.
  Fly   700 NLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEILEAHEKFLQTILVGCFVSNKAS 764

  Fly   802 LNRSI--------------FKLCKICLKYCEFIQITQRYFQDAELRS---------MVRDSADSS 843
            :..|:              ....|.|.|.....:...:..:.:|.:.         :.||.....
  Fly   765 VEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKI 829

  Fly   844 ESEQESLHCPQIETPLDPTDTFSERVRRFDLEFTQLLISFLKQINSMAKKNTADCFMNLV-HRIN 907
            .:|:..:.|..:|.              ...::.:.:.:||..:||....|     :.|. .|::
  Fly   830 FAEKMDIACRGLEV--------------IATDYEKAVSTFLMSLNSSDDPN-----LQLFGTRLD 875

  Fly   908 FNAFY 912
            ||.:|
  Fly   876 FNEYY 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	GCP_N_terminal	276..569	CDD:465456	67/330 (20%)
		GCP_C_terminal	572..912	CDD:461187	82/369 (22%)
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	81/411 (20%)
		GCP_C_terminal	549..880	CDD:461187	82/369 (22%)