Protein Alignment Grip84 and Tubgcp4

DIOPT Version :10

• Sequence 1: NP_728264.1
• Gene: Grip84 / 32946
• FlyBaseID: FBgn0026430
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_001386209.1
• Gene: Tubgcp4 / 362203
• RGDID: 1306924
• Length: 667
• Species: Rattus norvegicus
• Alignment Length: 761
• Identity: 146/761 - (19%)
• Similarity: 276/761 - (36%)
• Gaps: 227/761 - (29%)

  Fly   275 LLDELLHCLTGI---------RESLLVPQ-----KPIISAV--GLAKYDTDFDIHTHLDRSLTHQ 323
            ::.|||..|:|.         |..|.|.|     .|..::|  .|.:..||:...|......|..
  Rat     1 MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGH 65

  Fly   324 V--REILPLASYFMGVQKII--AATDGLGQVMNSLNEALQELTHDFYLIIVQAEQELRHNRLTLQ 384
            |  ::..|......|:..|.  |...||..|:....:||.:|..:|   :......:.|...:|.
  Rat    66 VQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEF---LADPHLSISHVNYSLD 127

  Fly   385 KLLYYLQPTMWVMHEVWSSLVIIQLSDSRDAEVL--TYLHERIKRLEGNKDAQQLIIGLVRKAAK 447
            :........|.|:.::.|..:       ...::|  .|.|. ...|...:.|.:.|:.:....
  Rat   128 QFQLLFPSVMVVVEQIKSQKI-------HGCQILETVYKHS-CGGLPPVRSALEKILAVCHGV-- 182

  Fly   448 PYMRMLQMWIQKGVIVDRHREFLV---------------------------------VDNEVIHR 479
             ..:.|..|:..|:::|:|.||.:                                 .|..:|..
  Rat   183 -MYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQMEEDEEDLGIGGLTGKQLRELQDLRLIEE 246

  Fly   480 DEL--PEHYSDDYWERRYTLRDEQIPSFL-AKYSDKILRTGKYLNVIRQCGKRVMPTQEMNLEFD 541
            :.:  |.       .::::||.|.:||:: .:.::|||..|:.:        ::...|.:||
  Rat   247 ENMLAPS-------LKQFSLRVEILPSYIPVRVAEKILFVGESV--------QMFENQNVNL--- 293

  Fly   542 PTSERHVSVI-NDAYYFAARM----------LLD------------------VLLTENDLMGHLQ 577
               .|..|:: |....|||.:          |:|                  :::.|:||:|.|:
  Rat   294 ---TRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDGIRSTVAEHLWKLMVEESDLLGQLK 355

  Fly   578 SVKRYLLLNQGDFTMQFMDACEDELTK----------NV-------------DHVLPMTLENLLG 619
            .:|.:.||.:|:....|:|..:..|..          ||             |::||     ||.
  Rat   356 IIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLP-----LLH 415

  Fly   620 LTLRISSARNDPYKDDLHCELLPYDLVTQMSKIMKKEENWQAQPRLDLSGLECFAFTYEVKWPCS 684
            ||:..   ....:|.|          .||..::..:|.:.:..|.   ||......:|:|:||..
  Rat   416 LTIEY---HGKDHKAD----------ATQPREVPSRETSPREPPS---SGWAALGLSYKVQWPLH 464

  Fly   685 LVLNHISISKYQMLFRQLFYCKHVERQLCKIWKENSIARQFEPQAASLYRAAFTLRQRMMNAIQN 749
            ::.....:.||.::|:.|...:.|:.:|...|......:..:.......:  :.||..|...:.|
  Rat   465 ILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQTDAVK--WRLRNHMAFLVDN 527

  Fly   750 LEYYMMIEIIEPNWHIFIEKMKTVENVDNVLRLHQDFLDSCLKNCMLTESSHLNRSIF----KLC 810
            |:||:.::::|..:...:.::.:..:.:::...|..||.:     :|.:|..|.:.:|    ::.
  Rat   528 LQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSN-----LLAQSFILLKPVFHCLNEIL 587

  Fly   811 KICLKYCEFIQITQRYFQDAELRSMVRDSADSSESEQESLHCPQIETPLDPTDT--FSERVRRFD 873
            .:|..:|..:.                                |...|||....  .|..|:.|.
  Rat   588 DLCHSFCSLVS--------------------------------QNLGPLDERGAAQLSILVKGFS 620

  Fly   874 LEFTQLLISFLK-----QINS-MAKKNTADCFMNLVHRINFNAFYT 913
            .: :.||...|.     |||| :|:         |:.|:::|.:||
  Rat   621 RQ-SSLLFKILSSVRNHQINSDLAQ---------LLLRLDYNKYYT 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	GCP_N_terminal	276..569	CDD:465456	69/379 (18%)
		GCP_C_terminal	572..912	CDD:461187	73/374 (20%)
Tubgcp4	NP_001386209.1	GCP_N_terminal	2..347	CDD:465456	69/379 (18%)
		GCP_C_terminal	350..655	CDD:461187	73/374 (20%)