Protein Alignment Grip84 and t-Grip91

DIOPT Version :10

• Sequence 1: NP_728264.1
• Gene: Grip84 / 32946
• FlyBaseID: FBgn0026430
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_723933.1
• Gene: t-Grip91 / 34931
• FlyBaseID: FBgn0028901
• Length: 1931
• Species: Drosophila melanogaster
• Alignment Length: 1057
• Identity: 205/1057 - (19%)
• Similarity: 378/1057 - (35%)
• Gaps: 303/1057 - (28%)

  Fly    15 ISESQSPLTPESIIREFRATSDRRLPACDLIKVLVS------ISEKRPNFAEVT-KEISHILQNK 72
            |||..|.::|.|.........|...|....|...||      ::|...:.:|:| |.:|.|||.:
  Fly   981 ISEGFSDISPMSTPGHPPDDQDELSPILGQISKTVSDVKINILNEVDKSLSEITVKSVSAILQKR 1045

  Fly    73 ------------------------------DPMYALLVFVERYSECKPVSESSSSTSLSAMGLPH 107
                                          .|:..:..|:..:::..|        |.|.:|.|:
  Fly  1046 KSKEYFSNQHKSQDFDYLTDDLSGESVVKVSPLKNVDRFISEWTQKNP--------SDSILGKPY 1102

  Fly   108 GNK---TSDVNSAAGSVPTTLAIASTSTILTTSQNVSGSTRLSLTQSQDFPTSTPVNCKKATESD 169
            ...   ||:.:..:.|........:::.||...::.:.....|...::.|.....:|.||...||
  Fly  1103 PKNLRYTSETSELSESSERESLSRNSNQILYLCKSCNAMLNYSEEVNKYFAGDFCINKKKFKVSD 1167

  Fly   170 TTPVVFVRRGPMDRNRGAGKDERNDLSVIKERVLNAVSDQS--LSGYRSVTNKTGNSPKS--MPN 230
                                  |||||.::.:.......|.  ::..|::.....::|..  .|:
  Fly  1168 ----------------------RNDLSNLERKFRQKWHHQRYVIAAPRAIIKSFKSNPAYGWSPD 1210

  Fly   231 DLVTLTDVPDEYRTHLLWEYYKVDGDKVPRA--EIAAMPLLSQESMLLDELLHCLTGIRESLLVP 293
            |    .:.||.|..  |.::::|.|.|..||  :|    |.:...:.|.::|..:  :|.:....
  Fly  1211 D----PNAPDFYEQ--LDQFFEVTGQKKYRAGCDI----LFASIQLRLSQVLKRI--VRHAPKNT 1263

  Fly   294 QKP-IISAVGLAKYDTDFDIHTHLDRSLTHQVR---EILPLASYFMGVQKIIAA---TDGLGQVM 351
            ..| :|:.||:|:          |::.||.:.|   |.:...|...|.|.:.|.   ||.|..:|
  Fly  1264 SFPDLITIVGVAQ----------LEQLLTRKERAAYESMRWQSRDKGDQDLSAESLFTDALHGMM 1318

  Fly   352 ---------NSLNEAL-------QELTHDFYLIIVQAE-----QELRHN--------------RL 381
                     :||...|       ||...:.||::....     :||:.:              |.
  Fly  1319 GYGSPHLKLSSLTGRLQLRSPHHQESISESYLLLALGHFGYFYRELKEHLARLAEQGDTALALRK 1383

  Fly   382 TLQKLLYYLQPTMWVMHEVWSSLVIIQLSDSRDAE------------------VLTYLHERIKRL 428
            .|||.|..|.....|.....|||:.: ...:||.:                  ::.||::...|.
  Fly  1384 CLQKYLLNLHQFYDVQKRNPSSLLSL-YRRTRDFQRNFEWLLEVFNNVQKAKSIVVYLYKESSRR 1447

  Fly   429 EGNKDAQQLIIGLVRKAAKPYMRMLQMWIQKGVIVDRHREFLVVDNEVIHRDELPEHYS--DDYW 491
            .|.:  :.|::..:|...:|.:..|.:|:..|.:.....:..|::.         ..||  |::|
  Fly  1448 TGYQ--RNLLLKWLRLVIQPLIYNLHIWLLNGRLPSTDHDMFVIEQ---------TKYSKVDEFW 1501

  Fly   492 ERRYTLR-------DEQIPSFLAKYSDKILRTGKYLNV-IRQCGKRVMPTQE---MNLEFDPTSE 545
            |:||.:.       |.|:...|......:..:.|||.: ...|    :|.:|   |.||......
  Fly  1502 EKRYRITESFSGIFDPQLSEILISVGKTMEYSEKYLAINFESC----VPRKEVRCMLLETFDKFL 1562

  Fly   546 RHVSVINDAYYFAARMLLDVLLTENDLMGHLQSVK-----------RYLLLNQGDFTMQFMDACE 599
            ||... ...|.|...:.|::   .:.::.:|:..|           :|::|...:|.|:|::|.|
  Fly  1563 RHGDQ-EPLYNFVRNLHLEI---SSKVLKYLRKTKINPEYLFSGLHKYIMLTDLNFIMEFINALE 1623

  Fly   600 DELTKNVDHVLPMTLENLLGLTLRISSARNDPYKDDLHCE--------LLPYDLVTQMSKIMKKE 656
            ..|.: .:....:.|.|.:...:...|.| |.|.|....|        :|.:.:.|
  Fly  1624 SVLGE-PESSFNIQLFNEMKNKMLHKSVR-DIYIDKSESEGSRCWSKLILRWKMPT--------- 1677

  Fly   657 ENWQAQPRLDLSGLEC-------FAFTYEVKWPCSLVLNHISISKYQMLFRQLFYCKHVERQLCK 714
             :|:|....|....|.       |.:.|       .|||. .:.:.|:.|:....|.:.|..
  Fly  1678 -HWRALLGEDSKAYEVIFKAMWRFHYVY-------YVLNE-RVHRQQIRFQNHIECTYFEGL--- 1730

  Fly   715 IWKENSIARQFEPQAASLYRAAFTLRQRMMNAIQNLEYYMMIEIIEPNWHIFIEKMKTVENVDNV 779
                |...:.|    :.|..|..    |:||.:  :||::.. ::||.:...:...:....||.:
  Fly  1731 ----NDTLKCF----SKLTNACL----RLMNVL--MEYFLDY-LLEPAFARLLWYCRNAITVDEL 1780

  Fly   780 LRLHQDFLDSCLKNCMLTES------------SHLNRSIFKLCKICLKYCEFI---------QIT 823
            |..::.:|.:.:...:.|::            ..|:...:|..::|....|::         .|.
  Fly  1781 LVANRKYLKTIILGSLQTKNLRKYLERLYDLILQLDNKHWKFLRLCQTSVEYVIRVRKEKPQSIF 1845

  Fly   824 QRYFQDAELR---------SMVRDSADSSE------------SEQESLHCPQIETPLDPTDTFSE 867
            ..|:::..|:         .::.:..|..:            ::.:||.  .:...|||...:.|
  Fly  1846 STYYRERMLQFRWTCQNYSDVINEMKDQFDLAMISFLLCLHLADDDSLR--SLAKRLDPEHYYME 1908

  Fly   868 RVRRFDL----EFTQLL 880
            :..|.||    ||.:.|
  Fly  1909 KDNRLDLVQYFEFRRKL 1925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	GCP_N_terminal	276..569	CDD:465456	77/365 (21%)
		GCP_C_terminal	572..912	CDD:461187	69/381 (18%)
t-Grip91	NP_723933.1	GCP_N_terminal	1312..1591	CDD:465456	60/298 (20%)
		GCP_C_terminal	<1690..1906	CDD:461187	39/243 (16%)