Protein Alignment Grip84 and Grip128

DIOPT Version :10

• Sequence 1: NP_728264.1
• Gene: Grip84 / 32946
• FlyBaseID: FBgn0026430
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_573030.2
• Gene: Grip128 / 32478
• FlyBaseID: FBgn0026433
• Length: 1092
• Species: Drosophila melanogaster
• Alignment Length: 795
• Identity: 146/795 - (18%)
• Similarity: 249/795 - (31%)
• Gaps: 269/795 - (33%)

  Fly   209 QSLSGYRSVTNKTGNSPKSMPNDLVTLTDVPDEYRTHLLWEYYKVDGDKVPRAEIAAMPLLSQES 273
            |.|..|....||   .|..  |.|:..|   .|:|.|                       .||
  Fly   466 QLLIAYEDRVNK---DPAK--NTLIRFT---IEFREH-----------------------FSQ-- 497

  Fly   274 MLLDELLHCLTGIRESLLVPQKP--IISAVGLAKYDTDFDIHTHLDRSLTHQVREILPLASYFMG 336
                  |..|..:.|.:::.:.|  |.||..|::      ::.|....:.||.   |..|..|:.
  Fly   498 ------LRLLRELAEDVILDKGPAHIRSAYLLSR------LYKHTLLQVPHQK---LATALLFIS 547

  Fly   337 VQKIIAATDGLGQVMNSLNEALQELTHDFYLIIVQAEQELRHNRLTLQKLLYYLQPTMWVMHEVW 401
            :::.....||..:     ..||::...:|
  Fly   548 LKRYCIIIDGWWR-----RAALEDHLREF------------------------------------ 571

  Fly   402 SSLVIIQLSDSRDAEVLTYLHERIKRLEGNKDAQQLIIGLVRK--AAKPYMRMLQMWIQKG---- 460
                |::.....||.  |..|.| ||..|.:| ..|::.:..|  :...|..:|:..::.|
  Fly   572 ----IVEFCYEEDAN--TRSHVR-KRNMGMED-DLLLVEIFNKLQSCPLYQLLLEHALESGETQD 628

  Fly   461 --VIVDRHREFLVVDNEVIHRDELPEHYSDDYWERRYTLRDEQIPSFLAK-----------YSDK 512
              ..|:...|.|..:||:    :||            :|.||....|.|:           |.|:
  Fly   629 LLCSVNTLSEMLTSNNEI----QLP------------SLHDELFTQFFAQLKVYCGADNTDYEDE 677

  Fly   513 ILRTGKY--LNVIRQCGKR--------VMPTQEMNLE-------FDPTSERHV------------ 548
            ......|  |.|..:.|.|        ..|..|..||       .:|....::
  Fly   678 PEPDKDYEDLTVCNRQGIRNHELFAIFTQPLVEQRLERQRERLKSNPVLMANILKRLERSTCLQL 742

  Fly   549 ---------SVINDAYYFAARMLLDVLLTENDLMGHLQSVKRYLLLNQGDFTMQFMDACEDELTK 604
                     .::....:.|....:.....|..:...::.::..:||.:....:.:.:|....:.|
  Fly   743 KSELPEALREILRRRQWLANEYAIRAYCKETQVAEKMRFLRHTMLLEKYYLFVPYYNALFVRMEK 807

  Fly   605 NVDHVLPMTLENLLGLTLRISSARNDPYKDDLHCELLPYDLVTQM-SKIMKKEENWQAQPRLDLS 668
            |....|...|.:.|...|.       |:...| ...|...|::|: |..:|..|
  Fly   808 NNSWALGSVLTSKLCAVLL-------PHYPQL-AHYLHVKLISQINSNSIKVYE----------- 853

  Fly   669 GLECFAFTYE-----VKWPCSLVLNHISISKYQMLFRQLFYCKHVERQLCKIWKENSI----ARQ 724
            .||.....:|     .:|   .:|....:..|..::|.:...|..      :||..::    ..:
  Fly   854 ALEAIELDFERPMAMHQW---YILTPAHMQDYNSVWRLMLKVKWA------VWKLENMQFLRRAR 909

  Fly   725 FEPQAASLYRAAFTLRQR------MMNAIQNLEYYMMIEIIEPNWHIFIEKMKTVENVDNVLRLH 783
            |.| .|.|.....|:|:.      ::..|.||..::| |.:...:.:.|.:.|   ||..:..:|
  Fly   910 FNP-CAPLDLIGLTIRRLEIVRFWLIFLINNLHAHIM-EAVSRQFELRIGECK---NVRELRIMH 969

  Fly   784 QDFLDSCLKNCMLTESSHLNR----SIFKL----------CKICL----KYCEFIQITQRYFQDA 830
            .:.|.....:||||:.....|    .||.|          |..|:    ..|..:.|:.
  Fly   970 DEHLAWLKTHCMLTDEFKAFRVALDQIFHLVYVLDMEWTTCASCMHDHDALCLDVTISD------ 1028

  Fly   831 ELRSMVRDSADSSESEQESLHCPQIETPLDPTDTFSERVRRFDLEFT---QLLISFLKQINSMAK 892
                   |..|.||:::.||....:           .:|...:|.:.   |:|...|   |::..
  Fly  1029 -------DGIDDSETQRRSLEYLAL-----------NQVAEIELTYIRCHQMLADIL---NTLVH 1072

  Fly   893 KNTADCFMNLVHRIN 907
            :|.......|...||
  Fly  1073 QNDHGFLSALEETIN 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	GCP_N_terminal	276..569	CDD:465456	59/351 (17%)
		GCP_C_terminal	572..912	CDD:461187	72/373 (19%)
Grip128	NP_573030.2	GCP5_NTD	25..130	CDD:439339
		GCP_N_terminal	371..>574	CDD:465456	34/200 (17%)
		GCP_C_terminal	<873..1082	CDD:461187	48/246 (20%)