Protein Alignment Grip84 and t-Grip128

DIOPT Version :10

• Sequence 1: NP_728264.1
• Gene: Grip84 / 32946
• FlyBaseID: FBgn0026430
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_729045.1
• Gene: t-Grip128 / 317930
• FlyBaseID: FBgn0052232
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 954
• Identity: 173/954 - (18%)
• Similarity: 320/954 - (33%)
• Gaps: 334/954 - (35%)

  Fly    17 ESQSPLTPESIIREFRATSDRRLPACDLIKVLVSISEKRPNFAEVTKEISHILQNKDPMYALLVF 81
            :||.|.:|..     :.|.|:....||.|:.|.|     ..:..:     |.::::.||
  Fly   179 KSQKPKSPRK-----KLTPDQIQRLCDEIRDLTS-----SKYGSL-----HTVRSQIPM------ 222

  Fly    82 VERYSECKPVSESSSSTSLSAMGLPHGNKTSDVNSAAGSVPTTLAI--ASTSTILTTSQNVSGST 144
                .:.||:..|..            |.:.::|....:|.....|  |.....|...||...:.
  Fly   223 ----EQSKPLDTSDY------------NYSRELNLGKVAVKENFTIKGAKMELELNVVQNKPSAE 271

  Fly   145 RLSLTQSQDFPTSTPVNCKKATESDTTPVVFVRRGPMDRNRGAGKDERN----DLSVIKERVLNA 205
            :.:|.   ||         ...|||....:                :.|    |:||..:  .:.
  Fly   272 KPALV---DF---------FKNESDMLYRI----------------QTNWWQVDISVYNQ--AHI 306

  Fly   206 VSDQSLSGYRSVTNKTGNSPKSMPNDLVTLTDVPDEYRTHLLWEYYKVDGDKVPRAEIAAMPLLS 270
            ::.....||..:.                         ...|||            ..|::..||
  Fly   307 LASNFCQGYADIL-------------------------IFQLWE------------SQASIRKLS 334

  Fly   271 QESMLLDELLHCLTGIRESLLVPQKPIISAVGLAKYDTDFDIHTHLDRSLTHQVREILPLASYFM 335
            :|..||.||:         :|........:..:...:.:|    ..|..||..::::
  Fly   335 EEHQLLSELI---------VLFFASANCRSFKILNDNWEF----RADEPLTCALKQL-------- 378

  Fly   336 GVQKIIAATDG--LGQVMNSLNEALQELTHDFYLIIVQAEQELRHNRL----------------T 382
                    .:|  ||:::.|    |:::.|...||...|.:.:|::||                .
  Fly   379 --------QEGPHLGEIIKS----LKQMRHLRELIETYAVKGIRYDRLKTLTFFSVALRQLLRPV 431

  Fly   383 LQKLLYY-------LQPTMWVMHEVWSS-------LVIIQLSDSRDAEVLTYLH--ERIKRLEG- 430
            ::.|:::       |:|.. :.|.:.:|       .::.:||.:::.|    ||  ..:|.|:.
  Fly   432 IEFLVHFERRLTSGLEPAT-LQHFIETSRGHLETIKLLYELSQNKNQE----LHSLRSLKTLDTL 491

  Fly   431 -NKDAQQ--------LIIGLVRKAAKPYMRMLQMWIQKGVIVDRHREFLVVDNEVIHRDELPEHY 486
             .|.:|:        |...|:....:.|.:.|..|...|...|.|.||   ..|.|..||..|
  Fly   492 FTKSSQKTQPKLLRSLSASLLLHTVRAYCKFLDNWWSTGDFADYHEEF---PFEKIVTDERTE-- 551

  Fly   487 SDDYWERRYTLRDEQIPSFLAKYSDKILRTGKYLNVIRQCGKRVMPTQEMNLEFDPTSERHVSVI 551
                    |.||                             |.:|.|:..|.|.....:||:...
  Fly   552 --------YVLR-----------------------------KSLMQTELQNSELFRIIQRHLLES 579

  Fly   552 ND--AYYFAARMLLDVLLTENDLMGH-LQSVKRYLLLNQGDFTMQFMDACEDELTK------NVD 607
            :|  |..:.:|.:.:.         | |..::..:.|:.     ..:||...|:..      ...
  Fly   580 SDGVAILYDSRTISEF---------HTLHGIEPEIRLHN-----SLIDAVIGEIAPYQIKAIEAS 630

  Fly   608 HVLPMTLENLL-----GLTLRISS----ARNDPYKDDLHC--ELLPYDLV----TQMSKIMKKEE 657
            |.:|..|:.|.     |:.....|    .|.||.|...|.  |||...|.    |.:::|:.:|
  Fly   631 HYVPDILQQLQSTDHDGIRRLFYSFHMETRPDPRKPAGHSINELLRNFLTCADYTPITEIISQE- 694

  Fly   658 NWQAQPRLDLSGLECFAFTYEVKWPCSLVLNHIS--ISKYQ--MLFRQLFYCKHVERQLCKIWKE 718
                             |...:.....||.::||  :.::|  .:.|.|       |.:..:|..
  Fly   695 -----------------FQRLLNRRTRLVNSYISGLLQEFQGYKVVRHL-------RSVFLLWNY 735

  Fly   719 NSIARQFEPQAASLYRAAFTLRQRMMNAIQNLEYYMMIE-----------IIEPNWHIFIEKMKT 772
            :....:||      :...|..|:.::.|...|::.::.:           :.|.:......:::.
  Fly   736 DHFRSEFE------FFFEFLRRKHLVEATNKLKHIVLCQDFTLGHMFKVCVTEAHPEFICLRVRN 794

  Fly   773 VENVDNVLRLHQ-DFLDSCLKNCMLTESSHLNRSIFKLCKI-CLKYCEFIQITQRYFQDAELRSM 835
            ...::.::...| |.::||.:..:     :||.|.::|..: ...||::    :|.|:  .|||
  Fly   795 DTLLNRIISQQQMDMMNSCFRLLL-----NLNFSHYRLNHLPPFHYCKY----ERLFK--ALRS- 847

  Fly   836 VRDSADSSESEQESLHCPQIETPLDPTDTFSERVRRFDLEFTQL 879
            ::.|..|...|..|..| ::...:...|:::..:..| ...|||
  Fly   848 IQISLISVFEEHLSHPC-KLFRKMQNLDSYNSELNEF-TSLTQL 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	GCP_N_terminal	276..569	CDD:465456	62/338 (18%)
		GCP_C_terminal	572..912	CDD:461187	66/347 (19%)
t-Grip128	NP_729045.1	GCP5_NTD	10..121	CDD:454848