Protein Alignment Grip84 and LOC1276259

DIOPT Version :10

• Sequence 1: NP_728264.1
• Gene: Grip84 / 32946
• FlyBaseID: FBgn0026430
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: XP_061505472.1
• Gene: LOC1276259 / 1276259
• VectorBaseID: AGAMI1_013802
• Length: 914
• Species: Anopheles gambiae
• Alignment Length: 981
• Identity: 359/981 - (36%)
• Similarity: 547/981 - (55%)
• Gaps: 138/981 - (14%)

  Fly     1 MSKPHALRGVLANLISESQSPLTPESIIREFRATSDRRLPACDLIKVLVSISEKRPNFAEVTKEI 65
            ||.....:.:||.|:.:|....|.::|:..| ...|.:.....|..:|..:.:..||.::.. ::
Mosquito     1 MSTEIVAKKLLAELVKKSGLTYTTDNIVTIF-LNRDGKYSNKRLATLLAQLFKPFPNGSKYV-DM 63

  Fly    66 SHILQNKDPMYALLVFVERYSECKPVSESSSSTSLSAMGLPHGNK-TSDVNSAAGSVPT---TLA 126
            ......|:...||::.:.|::              :.:...|..| .::|.|||.:|..   ::.
Mosquito    64 YAPANTKESYPALVMVLNRFA--------------NDLKTAHAEKAAANVASAAATVAAQEHSIK 114

  Fly   127 IASTSTILTTSQNVSGSTRLSLTQSQDFPTSTPVNCKKATESDTTPVVFVRRGPMDRNRGAGKDE 191
            ..::.|.:.|..:.....|:||.:      |.|::..:......||
Mosquito   115 SDTSGTAVPTVSSEPVHKRVSLFE------SPPLSSTRIIPDQVTP------------------- 154

  Fly   192 RNDLSVIKERVLNAVSDQSLSGYRSVTNKTGNSPKSMPNDLVTL---TDVPDEYR------TH-- 245
             .::..|||:::.|.|:.:       :|:..:|....|..::..   .:.|...|      :|
Mosquito   155 -ENVQEIKEKLVQATSNPA-------SNRLSSSTSLPPGSMMAAHHHHNYPSLSRPAGFEFSHRK 211

  Fly   246 ---LLW-----EYYKVDGDKVPRAEIAAMPLLSQESMLLDELLHCLTGIRESLLVPQKPIISAVG 302
               :.|     |.|.:..    :|.:||:|:.|||.::|.|:|:||.||:.:|:.|:|      |
Mosquito   212 APIVSWNFNYDELYPLQS----KANVAAIPVASQEPIVLKEVLNCLIGIKGTLITPRK------G 266

  Fly   303 LAKYDTD------FDIHTHLDRSLTHQVREILPLASYFMGVQKII---AATDGLGQVMNSLNEAL 358
            ....|.|      |.:...|..|....|.|:||||:.:..||..|   :.|:| |.|:.:|...|
Mosquito   267 ATTLDPDGALAVEFQLSNQLTESCRDMVVEVLPLAANYSAVQSFIEGASVTEG-GVVLQALRSVL 330

  Fly   359 QELTHDFYLIIVQAEQELRHNR-LTLQKLLYYLQPTMWVMHEVWSSLVIIQLSDSRDAEVLTYLH 422
            :.:..|:||.|.|.: :||..| |:||:|:.:|:|....|.|:.:::..|:.|::|..:||:.||
Mosquito   331 KTIMTDYYLSIAQLD-DLRCRRGLSLQRLIQFLKPVYPTMEELAATVSEIRRSNARGGQVLSLLH 394

  Fly   423 ERIKRLEGNKDAQQLIIGLVRKAAKPYMRMLQMWIQKGVIVDRHREFLVVDNEVIHRDELPEHYS 487
            :||....|...||::::.||..||.|:|.||::||.:|||.|..:||.:..:.:    ||.|:..
Mosquito   395 DRITAKSGTNHAQKVLVHLVESAAAPFMEMLELWIYRGVINDPQQEFFIDHSSM----ELTENEL 455

  Fly   488 DDYWERRYTLRDEQIPSFLAKYSDKILRTGKYLNVIRQC-GKRVMP------------------- 532
            .||||::||:|:|::|.||||::|.||||||||||:|.| |....|
Mosquito   456 VDYWEKQYTIRNEKVPCFLAKHADIILRTGKYLNVVRVCGGAEFQPGNANGGGGGGATTTTDLLN 520

  Fly   533 ---------TQEMNLEFDPTSERHVSVINDAYYFAARMLLDVLLTENDLMGHLQSVKRYLLLNQG 588
                     |....|::....:.::..|.:||.||:..||::::.:.||||.|.|||||.||.||
Mosquito   521 ASSATARTTTAVKRLQYAHFDQSYLDEIEEAYNFASSSLLNLIMNKYDLMGRLLSVKRYFLLQQG 585

  Fly   589 DFTMQFMDACEDELTKNVDHVLPMTLENLLGLTLRISSARNDPYKDDLHCELLPYDLVTQMSKIM 653
            ||..:||||.|::|.|:||.:.|:.|.|||.:||.:|||:.|.|.|||...||||.:|||:|||:
Mosquito   586 DFITEFMDAVEEDLRKSVDTLHPIRLANLLDVTLGLSSAKYDEYHDDLKTMLLPYGIVTQISKIV 650

  Fly   654 KKEENW--QAQPRLDLSGLECFAFTYEVKWPCSLVLNHISISKYQMLFRQLFYCKHVERQLCKIW 716
            ..|:.:  .......|.|:|||.|||:.:||.|:|||..:||||||:||||||.|:|||.||::|
Mosquito   651 NNEDAFVDTLSDTSQLKGVECFTFTYKAQWPVSIVLNLWTISKYQMIFRQLFYLKYVERILCRVW 715

  Fly   717 KENSIARQFEPQAASLYRAAFTLRQRMMNAIQNLEYYMMIEIIEPNWHIFIEKMKTVENVDNVLR 781
            ..|:..|||.|..|.|||:||||||:|:.|||:.|.|||||:||||||||.:.||.|:|:|:||.
Mosquito   716 IANNETRQFAPNPAKLYRSAFTLRQKMLIAIQSFESYMMIEVIEPNWHIFYQNMKQVKNIDDVLN 780

  Fly   782 LHQDFLDSCLKNCMLTESSHLNRSIFKLCKICLKYCEFIQITQRYFQDAELRSMVRDSAD---SS 843
            .||||||.|||||||||.. |.:.|..||.||:|:|:|:..:||:|.||||..|:....|   ||
Mosquito   781 YHQDFLDQCLKNCMLTEPD-LLKPIINLCNICIKFCDFLAESQRHFVDAELTCMLASGDDCSLSS 844

  Fly   844 ESEQESLHCPQIETPLDPTDTFSERVRRFDLEFTQLLISFLKQINSMAKKNTADCFMNLVHRINF 908
            ||:.|     |..|.:.||:||||||.:|..:||..|::.|::|..:|..:|::.|:||::||||
Mosquito   845 ESDYE-----QTATTMAPTETFSERVEQFRHDFTDQLMTLLRKIADVATLSTSERFINLIYRINF 904

  Fly   909 NAFYTD 914
            |::|::
Mosquito   905 NSYYSE 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip84	NP_728264.1	GCP_N_terminal	276..569	CDD:465456	115/331 (35%)
		GCP_C_terminal	572..912	CDD:461187	187/344 (54%)
LOC1276259	XP_061505472.1	None