Protein Alignment CG32532 and pitx1

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001035436.3
• Gene: pitx1 / 678598
• ZFINID: ZDB-GENE-060421-3623
• Length: 285
• Species: Danio rerio
• Alignment Length: 298
• Identity: 84/298 - (28%)
• Similarity: 119/298 - (39%)
• Gaps: 76/298 - (25%)

  Fly   436 MDSSSHHHTPAHTPPSR-----LSDHTISAEGAFKKLKPEPNSGLSTVSAGITSPGSGLSSLSQH 495
            :|.:|..|.|.....:|     .|..:...|.|.|:...|..|          ..|:
Zfish     3 VDMASSFHLPRSASSTRETLENTSSESSDTEAAEKERSVEQRS----------DDGN-------- 49

  Fly   496 AGHTPTTASCPTPAR-RRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKLNEARIQVWFQ 559
                   |..|...: ||.||.||.:||.||||.|.::.|||:..|||:|..|.|.|||::|||:
Zfish    50 -------ADDPKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFK 107

  Fly   560 NRRAKYRKQEKQLQKALAP-SVIPSCNGMMRNIQGYS-----------VSRGYQPYP-------H 605
            |||||:||:|:..|..|.. |.:|..:|:|   |.|.           .::|..|.|       .
Zfish   108 NRRAKWRKRERNQQMDLCKNSYLPQFSGLM---QPYDDVYPTYTYNNWTNKGLTPAPLSTKNFTF 169

  Fly   606 HNTMNRYPQDLFQMGASSYPGMTQPFSMAHSTNMGSVGVRQDSMGEFHG---------------- 654
            .|:|:...........||...|:....|.||...|......:::|..:|
Zfish   170 FNSMSPLTSQSMFSAPSSISSMSMASGMGHSAVPGMPTTGLNNIGNLNGIGGSTINPAMSSSTCP 234

  Fly   655 ----MSPED---EWYNKSLSALRMNSSHHPNLSAPMLQ 685
                :||..   :..|.||:.||:.|..||:.....||
Zfish   235 YGPPVSPYSVYRDTCNSSLATLRLKSKQHPSFGYSGLQ 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	33/55 (60%)
pitx1	NP_001035436.3	COG5576	8..>126	CDD:227863	50/142 (35%)
		Homeodomain	59..115	CDD:459649	33/55 (60%)
		OAR	247..263	CDD:461067	6/15 (40%)