Protein Alignment CG32532 and pitx2

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001017227.1
• Gene: pitx2 / 549981
• XenbaseID: XB-GENE-482492
• Length: 345
• Species: Xenopus tropicalis
• Alignment Length: 320
• Identity: 88/320 - (27%)
• Similarity: 126/320 - (39%)
• Gaps: 103/320 - (32%)

  Fly   441 HHHTPAHTPPSRLSDHTISAEGAFKKLKPEPNSGLSTVSAGITSPGSGLSSLSQHAG-------- 497
            |||...|....:               :|:|.: ::.||..        |||.|.:|
 Frog    37 HHHQQHHHQQHQ---------------QPQPQA-VTLVSMA--------SSLGQRSGECKARLEV 77

  Fly   498 HTPTTASCPTPA-----------------------RRRHRTTFTQEQLAELEAAFAKSHYPDIYC 539
            ||.:..|.|..|                       :||.||.||.:||.||||.|.::.|||:..
 Frog    78 HTISDTSSPEAADKDKSHQSKNEDSSTDDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMST 142

  Fly   540 REELARTTKLNEARIQVWFQNRRAKYRKQEKQLQKALAPSVI-PSCNGMMRNIQGY--------- 594
            |||:|..|.|.|||::|||:|||||:||:|:..|..|..:.. |..||:|   |.|
 Frog   143 REEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLM---QPYDDMYPSYSY 204

  Fly   595 ---------SVSRGYQPYPHHNTMNRYP---QDLFQMGASSYPGMTQPFSMAHSTNMGSVGVRQD 647
                     |.|...:.:|..|:||..|   |.:|. ..:|...|:....|..|...|..|...:
 Frog   205 NNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFS-SPNSISSMSMSSGMVPSAVTGVPGSGLN 268

  Fly   648 SMGEFHGMS----------------PEDEWY------NKSLSALRMNSSHHPNLSAPMLQ 685
            |:...:.:|                |....|      |.||::||:.:..|.:.....:|
 Frog   269 SLNNLNNLSNPSLNTAVPTSACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQ 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	33/55 (60%)
pitx2	NP_001017227.1	Homeodomain	114..170	CDD:459649	33/55 (60%)
		OAR	303..320	CDD:461067	5/16 (31%)