Protein Alignment CG32532 and PRRX2

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_057391.1
• Gene: PRRX2 / 51450
• HGNCID: 21338
• Length: 253
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 87/282 - (30%)
• Similarity: 117/282 - (41%)
• Gaps: 74/282 - (26%)

  Fly   423 DFSALYSGLPTPGMDSSSHHHTPAHTP-----------PSRLSD-HTISAEGAFKKLKPEPNSGL 475
            |..||..|.|.|         .||..|           .|.|.| ..::|.|   :|...|.:..
Human    11 DKPALGPGPPPP---------PPALGPGDCAQARKNFSVSHLLDLEEVAAAG---RLAARPGARA 63

  Fly   476 STVSAGITSPGSGLSSLSQHAGHTPTTASCPTPAR----------RRHRTTFTQEQLAELEAAFA 530
            .........| ||.||.|:.|   |....||:|.|          ||:||||...||..||..|.
Human    64 EAREGAAREP-SGGSSGSEAA---PQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFE 124

  Fly   531 KSHYPDIYCREELARTTKLNEARIQVWFQNRRAKYRKQEKQLQKALAPSVIPSCNGMMRNIQGYS 595
            ::||||.:.||||||...|:|||:||||||||||:|:.|:.:..:.:.|::.|.:      |..:
Human   125 RTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYS------QEAA 183

  Fly   596 VSRGYQPYPHHNTMNRYPQDLFQMGASSYPGMTQPFSMAHSTNMGSVGVRQDSMGEFHGMSPEDE 660
            :.:...|.|     .....|.....|||      |:|.....:.||.|             |...
Human   184 IEQPVAPRP-----TALSPDYLSWTASS------PYSTVPPYSPGSSG-------------PATP 224

  Fly   661 WYN--KSLSALRMN----SSHH 676
            ..|  .|:::||:.    |.||
Human   225 GVNMANSIASLRLKAKEFSLHH 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	35/55 (64%)
PRRX2	NP_057391.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33		9/30 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	55..113		20/61 (33%)
		Homeodomain	109..161	CDD:459649	32/51 (63%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	230..243		3/12 (25%)