Protein Alignment CG32532 and PAX4

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001353039.1
• Gene: PAX4 / 5078
• HGNCID: 8618
• Length: 351
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 85/335 - (25%)
• Similarity: 117/335 - (34%)
• Gaps: 127/335 - (37%)

  Fly   292 HSLGLSPQSSADSQQFNIFPAIFSRQLNFSAGGQGGKLSMDELRP-----------NLVGGLLG- 344
            |..|:|..    :|...:|  :..|.|......|..:|::..:||           ..|..:||
Human     2 HQDGISSM----NQLGGLF--VNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGR 60

  Fly   345 -LQQGLLEDHASMQHGGVGQDTKFMSFQDQRLMGIGGSHEN--------RLLSLASSV------- 393
             .:.|:||.                       .|||||...        |:..|....
Human    61 YYRTGVLEP-----------------------KGIGGSKPRLATPPVVARIAQLKGECPALFAWE 102

  Fly   394 ---QDTRSPITTLEKSSS-SSLNHQRKCSSTPEDFSALYSGLPTPGMDSSSHHHTPAHTPPSRLS 454
               |.....:.|.:|:.| ||:|  |...:..||     .|||...:.|      ||...|:.|:
Human   103 IQRQLCAEGLCTQDKTPSVSSIN--RVLRALQED-----QGLPCTRLRS------PAVLAPAVLT 154

  Fly   455 DHTISAEGAFKKLKPEPNSGLSTVSAGITSPGSGLSSLSQHAGHTPTTASCPTPARRRHRTTFTQ 519
                            |:||..|...  |.||:|                      .|:||.|:.
Human   155 ----------------PHSGSETPRG--THPGTG----------------------HRNRTIFSP 179

  Fly   520 EQLAELEAAFAKSHYPDIYCREELARTTKLNEARIQVWFQNRRAKYRKQEK-----QLQKA---- 575
            .|...||..|.:..|||...|.:||..|.|.|..::|||.|||||:|:|||     ||..|
Human   180 SQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGL 244

  Fly   576 ----LAPSVI 581
                :||.:|
Human   245 TVPRVAPGII 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	25/55 (45%)
PAX4	NP_001353039.1	PAX	5..129	CDD:128645	31/154 (20%)
		Homeodomain	172..227	CDD:459649	25/54 (46%)