Protein Alignment CG32532 and OTX2

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_068374.1
• Gene: OTX2 / 5015
• HGNCID: 8522
• Length: 297
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 75/231 - (32%)
• Similarity: 103/231 - (44%)
• Gaps: 50/231 - (21%)

  Fly   463 AFKKLKPEPNSGLSTVSAGITSPGSGLSSLSQHAGHTPTTASCP--TPAR-RRHRTTFTQEQLAE 524
            ::.|..|...:|||..:       ||:..|....|:....||||  ||.: ||.|||||:.||..
Human     3 SYLKQPPYAVNGLSLTT-------SGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60

  Fly   525 LEAAFAKSHYPDIYCREELARTTKLNEARIQVWFQNRRAKYRKQEKQLQKALAPSVIPSCNGMMR 589
            |||.|||:.||||:.|||:|....|.|:|:||||:|||||.|:|::|.|           ||...
Human    61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ-----------NGGQN 114

  Fly   590 NIQGYSVSRGYQPYPHHNTMNRYPQDLFQMGASSYPGMTQPFSMAHSTNMGSVGVRQDSMGEFHG 654
            .:         :|.....:..|        ..||..|.:..|:...||::.::.         ..
Human   115 KV---------RPAKKKTSPAR--------EVSSESGTSGQFTPPSSTSVPTIA---------SS 153

  Fly   655 MSPEDEWYNKSLSALR---MNSSHHPNLSAPMLQYQ 687
            .:|...|...|:|.|.   ..||.....|.||...|
Human   154 SAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQ 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	35/55 (64%)
OTX2	NP_068374.1	Homeodomain	47..102	CDD:459649	35/54 (65%)
		TF_Otx	161..242	CDD:427350	9/29 (31%)