Protein Alignment CG32532 and OTX1

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_055377.1
• Gene: OTX1 / 5013
• HGNCID: 8521
• Length: 354
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 68/255 - (26%)
• Similarity: 103/255 - (40%)
• Gaps: 58/255 - (22%)

  Fly   486 GSGLSSLSQHAGHTPTTASCPTPAR-RRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKL 549
            |.||:..:....| |:.....||.: ||.|||||:.||..|||.|||:.||||:.|||:|....|
Human    14 GLGLAGPAMDLLH-PSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINL 77

  Fly   550 NEARIQVWFQNRRAKYRKQEK-----------------------QLQKALAPSVIPSCNGMMRNI 591
            .|:|:||||:|||||.|:|::                       :......|..:.|......:.
Human    78 PESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSA 142

  Fly   592 QGYSVS--------RGYQPYPHHNTMNRYPQDLFQMGASSYPG-------MTQPFSMAHSTN--M 639
            ...|.:        .|..|....::::..........||..||       :.:|.:...:|:  .
Human   143 SSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQ 207

  Fly   640 GSVGVRQDSMGEFHGMS-------------PEDEWY---NKSLSALRMNSSHHPNLSAPM 683
            .||.....:....:.||             |...::   :.|.....|:|.|||:..:||
Human   208 RSVAAGAATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPM 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	35/55 (64%)
OTX1	NP_055377.1	Homeodomain	39..95	CDD:459649	35/55 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..146		6/54 (11%)
		TF_Otx	178..274	CDD:427350	19/90 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..305		6/11 (55%)