Protein Alignment CG32532 and PHOX2A

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001412025.1
• Gene: PHOX2A / 401
• HGNCID: 691
• Length: 312
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 78/262 - (29%)
• Similarity: 95/262 - (36%)
• Gaps: 74/262 - (28%)

  Fly   409 SSLNHQRKCSSTPE-----DFSAL-------YSGLPTPGMDSSSHHHTPAHTPPSRLSDHTISAE 461
            |.||....|.:..|     ||.|.       ||.| .|..        ||..||......:..|.
Human     4 SYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPL-RPAF--------PAAGPPCPALGSSNCAL 59

  Fly   462 GAFKKLKPEPNSGLSTVSAGITSPGSGLSSLSQHAGHTPTTASCPTPARRRHRTTFTQEQLAELE 526
            ||.:..:|.|   .|.|........|||....:               :||.|||||..||.|||
Human    60 GALRDHQPAP---YSAVPYKFFPEPSGLHEKRK---------------QRRIRTTFTSAQLKELE 106

  Fly   527 AAFAKSHYPDIYCREELARTTKLNEARI----------------------------QVWFQNRRA 563
            ..||::||||||.|||||....|.|||:                            |||||||||
Human   107 RVFAETHYPDIYTREELALKIDLTEARVQDLTRALRPRADPVRSPTLVQADWPLCPQVWFQNRRA 171

  Fly   564 KYRKQEKQLQKALAPSVIPSCNGMMRNIQGYSVSRGYQPYPHHNTMNRYPQDLFQMGASSYPGMT 628
            |:||||:......|.....:..|..|.......|:       .:|.:..|.....:.....||:.
Human   172 KFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSK-------ESTCSPTPDSTASLPPPPAPGLA 229

  Fly   629 QP 630
            .|
Human   230 SP 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	39/83 (47%)
PHOX2A	NP_001412025.1	Homeodomain	91..175	CDD:459649	39/83 (47%)