Protein Alignment CG32532 and ALX3

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 86/301 - (28%)
• Similarity: 123/301 - (40%)
• Gaps: 92/301 - (30%)

  Fly   432 PTPGMDSSSHHHTPAHTPPSRLSDHTISAEGAFKKL----KPEPNSGLSTVSAGITSPGSGLSSL 492
            |.|.::....:..||.      ::...|...:|.:|    :..|..|.|.:..   |||..|:||
Human    77 PGPALNGGHFYEGPAE------AEEKTSKAASFPQLPLDCRGGPRDGPSNLQG---SPGPCLASL 132

  Fly   493 SQHAGHTPTTASCP--------TPARRRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKL 549
                 |.|.:...|        ...:||:||||:..||.|||..|.|:||||:|.||:||..|.|
Human   133 -----HLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDL 192

  Fly   550 NEARIQVWFQNRRAKYRKQEK--QLQKALAP-------SVIPSCNGMMRNIQGYSVSRGYQPYPH 605
            .|||:||||||||||:||:|:  ::|:...|       ||:|..:.
Human   193 TEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDS------------------- 238

  Fly   606 HNTMNRYPQ---DLFQMGASSYPG-------------MTQPFSMAHSTNMGSVGVRQDSMG---- 650
                  :||   .|:....|..||             ...|:|..|.:..|.:||...|..
Human   239 ------HPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGI 297

  Fly   651 -EFHGMSP-----------EDEWYNKSLSALRMNSSHHPNL 679
             ..||..|           :.::.:.||.:||:.....|.|
Human   298 YSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPPGL 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	37/55 (67%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		5/32 (16%)
		PRK12323	<13..131	CDD:481241	14/62 (23%)
		Homeodomain	154..210	CDD:459649	37/55 (67%)