Protein Alignment CG32532 and Otx2

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001273410.1
• Gene: Otx2 / 18424
• MGIID: 97451
• Length: 297
• Species: Mus musculus
• Alignment Length: 231
• Identity: 76/231 - (32%)
• Similarity: 104/231 - (45%)
• Gaps: 50/231 - (21%)

  Fly   463 AFKKLKPEPNSGLSTVSAGITSPGSGLSSLSQHAGHTPTTASCP--TPAR-RRHRTTFTQEQLAE 524
            ::.|..|...:|||..:       ||:..|....|:....||||  ||.: ||.|||||:.||..
Mouse     3 SYLKQPPYAVNGLSLTT-------SGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60

  Fly   525 LEAAFAKSHYPDIYCREELARTTKLNEARIQVWFQNRRAKYRKQEKQLQKALAPSVIPSCNGMMR 589
            |||.|||:.||||:.|||:|....|.|:|:||||:|||||.|:|::|.|           ||...
Mouse    61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ-----------NGGQN 114

  Fly   590 NIQGYSVSRGYQPYPHHNTMNRYPQDLFQMGASSYPGMTQPFSMAHSTNMGSVGVRQDSMGEFHG 654
            .:         :|....::..|        ..||..|.:..||...||::.::.         ..
Mouse   115 KV---------RPAKKKSSPAR--------EVSSESGTSGQFSPPSSTSVPTIA---------SS 153

  Fly   655 MSPEDEWYNKSLSALR---MNSSHHPNLSAPMLQYQ 687
            .:|...|...|:|.|.   ..||.....|.||...|
Mouse   154 SAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQ 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	35/55 (64%)
Otx2	NP_001273410.1	Homeodomain	47..102	CDD:459649	35/54 (65%)
		TF_Otx	161..242	CDD:427350	9/29 (31%)