Protein Alignment CG32532 and Hhex

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_032271.1
• Gene: Hhex / 15242
• MGIID: 96086
• Length: 271
• Species: Mus musculus
• Alignment Length: 210
• Identity: 53/210 - (25%)
• Similarity: 80/210 - (38%)
• Gaps: 63/210 - (30%)

  Fly   427 LYSGLPTPGMDSSSHHHTPAHTPPSRLSDHTISAEGAFKKLK----PEPNSGLSTVSAGITS--- 484
            ||:  |||.:.       |||..|..:.|  |...|......    |.|||..:::.:...:
Mouse    18 LYA--PTPLLQ-------PAHPTPFYIDD--ILGRGPAAPTPTPTLPSPNSSFTSLVSSYRTPVY 71

  Fly   485 ------------PGSGLSSLSQHAGH------TPTTASCPTPARRRH------------------ 513
                        |.:.|::....:|.      .|.|.:..|.|..||
Mouse    72 EPTPVHPAFSHHPAAALAAAYGPSGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLH 136

  Fly   514 -----RTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKLNEARIQVWFQNRRAKYR--KQE-- 569
                 :..|:.:|..|||..|....|.....|:.||:..:|:|.:::.||||||||:|  |||
Mouse   137 KRKGGQVRFSNDQTVELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENP 201

  Fly   570 KQLQKALAPSVIPSC 584
            :..:|....|:..||
Mouse   202 QSNKKDALDSLDTSC 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	23/80 (29%)
Hhex	NP_032271.1	Interaction with SOX13. /evidence=ECO:0000250|UniProtKB:Q03014	1..138		25/130 (19%)
		Required for WNT signaling induction. /evidence=ECO:0000250|UniProtKB:Q03014	138..271		28/79 (35%)
		Homeodomain	143..195	CDD:459649	20/51 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..271		7/22 (32%)