Protein Alignment CG32532 and DBX1

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001025036.2
• Gene: DBX1 / 120237
• HGNCID: 33185
• Length: 343
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 82/333 - (24%)
• Similarity: 118/333 - (35%)
• Gaps: 66/333 - (19%)

  Fly   373 QRLMGIGGSHENRLLSLASSVQDTRSPITTLEKSSSSSLNHQRKCSSTP-EDFSALYSGLPTPGM 436
            |.|......|.:.|:.  ..::.:|.|........::|::..|:.:.|. .|..|...|.|.||.
Human    27 QSLQSAFSGHSSFLVE--DLIRISRPPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGS 89

  Fly   437 DSSSHHHTPAHTPPSRLSDHTISAEGAFKKLKPEPNSGLSTVSAGITSPG--------------- 486
            ....       :||:..|.   ::|..|  ||...|:.||:.....|||.
Human    90 RRGG-------SPPTAFSP---ASETTF--LKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYF 142

  Fly   487 ---------SGLSSLSQHAGHTPTTASCPTPAR---RR---HRTTFTQEQLAELEAAFAKSHY-- 534
                     |.....|......|.|.|.|..||   ||   .|..|:..|...||..|.|..|
Human   143 EGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYIS 207

  Fly   535 -PDIYCREELARTTKLNEARIQVWFQNRRAKYRK------------QEKQLQKALAPSVIPSCNG 586
             ||   |::||....|.::::::||||||.|:|.            :|:.|...|.|.  |..:.
Human   208 KPD---RKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPH--PDLSD 267

  Fly   587 MMRNIQGYSVSRGYQPYPHHNTMNRYPQDLFQMGASSYPGMTQPFSMAHSTNMGSVGVRQDSMGE 651
            :.:...|..........|.|........|...:.....||...| |.|||::.|......||..|
Human   268 VGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPP-SPAHSSSPGKPSDFSDSEEE 331

  Fly   652 FHGMSPED 659
            ..|...|:
Human   332 EEGEEQEE 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	23/61 (38%)
DBX1	NP_001025036.2	PRK12323	<49..182	CDD:481241	34/144 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..100		11/50 (22%)
		Homeodomain	184..238	CDD:459649	21/56 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..343		22/103 (21%)