Protein Alignment CG32532 and Pitx1

DIOPT Version :10

• Sequence 1: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_446076.1
• Gene: Pitx1 / 113983
• RGDID: 69253
• Length: 315
• Species: Rattus norvegicus
• Alignment Length: 298
• Identity: 85/298 - (28%)
• Similarity: 119/298 - (39%)
• Gaps: 60/298 - (20%)

  Fly   432 PTPGMDSSSHHHTPAHTPPSRLSDHTISAEGAFKKLKPEPNSGLSTV--SAGITSPGSGLSSLSQ 494
            |.|..|.....|. |.|...|......::|.:...|..:...|.:.|  ..|..|.|.|
  Rat    21 PPPPHDMGPSFHL-ARTADPREPLENSASESSDADLPDKERGGEAKVPEDGGAGSAGCG------ 78

  Fly   495 HAGHTPTTASCPTPAR----RRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKLNEARIQ 555
                     |...||:    ||.||.||.:||.||||.|.::.|||:..|||:|..|.|.|.|::
  Rat    79 ---------SAEDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVR 134

  Fly   556 VWFQNRRAKYRKQEKQLQKALAP-SVIPSCNGMMRNIQGYSVSRGYQ----------PYP----- 604
            |||:|||||:||:|:..|..|.. ..:|..:|:::..:....:.||.          |.|
  Rat   135 VWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAAGYSYNNWAAKSLAPAPLSTKS 199

  Fly   605 --HHNTMNRYPQDLFQMGASSYPGMTQPFSMAHSTNMGSVGVRQDSMGEFHG------MSPEDEW 661
              ..|:|:...........||...||.|.||...:..|......:::....|      |||....
  Rat   200 FTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGSVPGMPNSGLNNINNLTGSSLNSAMSPGACP 264

  Fly   662 Y--------------NKSLSALRMNSSHHPNLSAPMLQ 685
            |              |.||::||:.|..|.:.....||
  Rat   265 YGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQ 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	32/55 (58%)
Pitx1	NP_446076.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..103		26/97 (27%)
		Homeodomain	90..146	CDD:459649	32/55 (58%)
		Interaction with PIT-1. /evidence=ECO:0000250	149..280		23/130 (18%)
		OAR	277..294	CDD:461067	6/16 (38%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	281..294		5/12 (42%)
		Nuclear localization signal. /evidence=ECO:0000255	287..291		1/3 (33%)