Protein Alignment CoRest and rcor1

DIOPT Version :9

• Sequence 1: NP_001188671.1
• Gene: CoRest / 32941
• FlyBaseID: FBgn0261573
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_012824008.1
• Gene: rcor1 / 733956
• XenbaseID: XB-GENE-5727159
• Length: 434
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 178/596 - (29%)
• Similarity: 269/596 - (45%)
• Gaps: 209/596 - (35%)

  Fly    12 VRNGRRSRGPSPNTHTTGGVTNSASLVGSGNNSGHSGNANANEKTTTAVPGAGTPESSDDDNSTK 76
            |...||.|..:.|:.:.|...|       |:||...|::::               ||||:
 Frog    11 VSGKRRGRNNAANSKSLGTSVN-------GSNSWEEGSSSS---------------SSDDE---- 49

  Fly    77 RNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVWSPTKEIPDLKLEEYISV 141
            :.|..          :|||..:|||.|....|..:..::.....:|||||.:.:.:.||:|||||
 Frog    50 QGGGG----------MRVGLQFQAVVPEFDQEVAKTCQERENLGMLVWSPNQNLSEAKLDEYISV 104

  Fly   142 AKEKYGYNGEQALGMLFWHKHDLERAVMDLANFTPFPDEWTIEDKVLFEQAFQFHGKSFHRIRQM 206
            ||||:|||.||||||||||||::|:::.||.||||||||||:||||||||||.||||:||||:||
 Frog   105 AKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM 169

  Fly   207 LPDKSIASLVKYYYSWKKTRHRSSAMDRQEKAIKAVVKDGSENGSEVGSNEESDNDDKKGHGTNS 271
            |||||||||||:||||||||.::|.|||..:..|.                     :::|.|
 Frog   170 LPDKSIASLVKFYYSWKKTRSKTSVMDRHARKQKR---------------------EREGSG--- 210

  Fly   272 TINTIDATTTSTNNSTTNSNTTTPANIIANTINSNHSSSNSGGGGNINNNGEENIQAVGGSNTIS 336
                                                                :.|:...|:|.:
 Frog   211 ----------------------------------------------------DEIEEANGANPV- 222

  Fly   337 NTSNNDMDAEQLSLFAGNAQIEEMMALGLAADRAIGANGGNNNNNGEMGGDPGLMRRMVVGGFCK 401
                 |::.||                                        |...::.|
 Frog   223 -----DIEIEQ----------------------------------------PKEAKKEV------ 236

  Fly   402 ICNVVCHVLHDSPLGRMCKSCHTHWRRTGNRRPISGPEGNAPRRSTHNCAATADRSKRKPPKGMY 466
                                          .:|.:.|.   .::..|...| .:|:||||||||:
 Frog   237 ------------------------------PKPDTSPH---IKKEKHPSQA-KNRAKRKPPKGMF 267

  Fly   467 INHDDLTALASCGN-PSLYLAERERKLTALMAEIQKNRQVMEQLDKECETINVDDVLSKPAAANT 530
            ::.:|:.|:::..| .:..|...:.:|.::..:||..:|....| ||.....:|:.       ..
 Frog   268 LSQEDVQAVSANANAATTVLRHLDMELVSIKRQIQNIKQTNSSL-KENLQGGIDEY-------RI 324

  Fly   531 ESAQPRISARWLPDEIQVALLAIREYGKNFPTIAKVVATKTEAHVRTFYLNNRRRYNLDQIVKEY 595
            :....:::|||..:|..:|:.|||:||::|..|:.|:..|:...|:.|::|.|||:|:||:::|:
 Frog   325 QEVSQKLNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDQVLQEW 389

  Fly   596 EA--GKSEESG 604
            ||  ||:||:|
 Frog   390 EAEHGKTEENG 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	21/51 (41%)
		SANT	179..225	CDD:197842	40/45 (89%)
		SANT	180..224	CDD:304392	38/43 (88%)
		SANT	540..582	CDD:238096	15/41 (37%)
rcor1	XP_012824008.1	ELM2	55..107	CDD:366648	21/51 (41%)
		SANT	143..187	CDD:389774	38/43 (88%)
		RSC8	<220..>368	CDD:227584	45/241 (19%)
		Myb_DNA-binding	334..377	CDD:365977	16/42 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11393
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32246
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2645
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287298at33208
OrthoFinder	1	1.000	-	-		FOG0001182
OrthoInspector	1	1.000	-	-		otm48495
Panther	1	1.100	-	-	O	PTHR16089
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3377
SonicParanoid	1	1.000	-	-		X1336
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100