Protein Alignment CoRest and Rcor3

DIOPT Version :10

• Sequence 1: NP_001188671.1
• Gene: CoRest / 32941
• FlyBaseID: FBgn0261573
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: NP_001128457.1
• Gene: Rcor3 / 684192
• RGDID: 1593864
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 655
• Identity: 195/655 - (29%)
• Similarity: 289/655 - (44%)
• Gaps: 206/655 - (31%)

  Fly    15 GRRSRGPSPNTHTTGGVTNSASLVGSGNNSGHSGNANANEKTTTAVPGAGTPESSDDDNSTKRNG 79
            |...:||.     ..|.:.||:  |...:....|.::||.....:.|.:|.  ||||::.
  Rat     3 GMMEKGPE-----LLGKSRSAN--GGAKSPAGGGGSSANGGLHFSEPESGC--SSDDEHG----- 53

  Fly    80 KSKAKQSEYEEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVWSPTKEIPDLKLEEYISVAKE 144
                     :..:|||.:|||..|...|.|.:..::.| ..:|||||...|||.||:||:::|||
  Rat    54 ---------DVGMRVGAEYQARIPEFDPGATKYTDKDN-GGMLVWSPYHSIPDAKLDEYVAIAKE 108

  Fly   145 KYGYNGEQALGMLFWHKHDLERAVMDLANFTPFPDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPD 209
            |:|||.||||||||||||::|:::.||.||||||||||:||||||||||.|||||||||:|||||
  Rat   109 KHGYNVEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPD 173

  Fly   210 KSIASLVKYYYSWKKTRHRSSAMDRQEKAIKAVVKDGSENGSEVGSNEESDNDDKKGHGTNSTIN 274
            |:|||||||||||||||.|:|.||||.:.:......|           :||:|.::.|
  Rat   174 KTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQG-----------DSDDDVEEPH------- 220

  Fly   275 TIDATTTSTNNSTTNSNTTTPANIIANTINSNHSSSNSGGGGNINNNGEENIQAVGGSNTISNTS 339
                                       .::.|.|..:.........|.|:.:|          ||
  Rat   221 ---------------------------PMDGNDSDYDPKKEAKREGNSEQPVQ----------TS 248

  Fly   340 NNDMDAEQLSLFAGNAQIEEMMALGLAADRAIGANGGNNNNNGEMGGDPGLMRRMVVGGFCKICN 404
                     .:..|..:.:.:.
  Rat   249 ---------KIGLGRREYQSLQ------------------------------------------- 261

  Fly   405 VVCHVLHDSPLGRMCKSCHTHWRRTGNRRPISGPEGNAPRRSTHNCAATADRSKRKPPKGMYINH 469
                              |.|                      |     :.|||.:||||||:..
  Rat   262 ------------------HRH----------------------H-----SQRSKCRPPKGMYLTQ 281

  Fly   470 DDLTALASCGN-PSLYLAERERKLTALMAEIQKNRQVMEQLDKECETINVDDVLSKPAAANTESA 533
            :|:.|::...| .:..|.:.:.:|.:|..::|..:||...|.::.|. .:::.  ||..:|
  Rat   282 EDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNSALKQKMEG-GIEEF--KPPESN---- 339

  Fly   534 QPRISARWLPDEIQVALLAIREYGKNFPTIAKVVATKTEAHVRTFYLNNRRRYNLDQIVKEYEAG 598
             .:|:|||..:|..:|:..:|:|||:|..||.|:..||...|:.|::|.|||:||:::::|:||
  Rat   340 -QKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEA- 402

  Fly   599 KSEESGAEEQTEPAVDAAAAGAATASAPSAADSTSAASATADRKQSTENSNNGVETMQESLPKKE 663
               |.|.:             |:.|...:..:.|.:||.....|.:.|..    |.....:|:..
  Rat   403 ---EQGTQ-------------ASNADTSALGEETKSASNVPSGKSTDEEE----EAQTPQVPRTL 447

  Fly   664 DPKKP 668
            .|..|
  Rat   448 GPSPP 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:460214	23/51 (45%)
		SANT	180..224	CDD:473887	39/43 (91%)
		Myb_DNA-binding	540..583	CDD:459731	17/42 (40%)
Rcor3	NP_001128457.1	ELM2	57..108	CDD:460214	23/51 (45%)
		SANT	144..188	CDD:473887	39/43 (91%)
		Myb_DNA-binding	345..388	CDD:459731	17/42 (40%)